S
Sandra D. O'Dell
Researcher at King's College London
Publications - 53
Citations - 1766
Sandra D. O'Dell is an academic researcher from King's College London. The author has contributed to research in topics: Population & Metabolic syndrome. The author has an hindex of 24, co-authored 53 publications receiving 1692 citations. Previous affiliations of Sandra D. O'Dell include St George's, University of London & St George's Hospital.
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Journal ArticleDOI
Molecules in focus Insulin-like growth factor II (IGF-II)
Sandra D. O'Dell,Ian N.M. Day +1 more
TL;DR: In the general adult population, the IGF2-INS gene cluster may also influence body weight, in which case IGF-II function could become a target for therapeutic intervention in obesity.
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Positive associations between single nucleotide polymorphisms in the IGF2 gene region and body mass index in adult males
TL;DR: Association with 11 more markers, including seven novel single nucleotide polymorphisms (SNPs), spanning >30 kb across the IGF2 gene is tested, strongly suggesting that IGF2 genetic variation is a significant determinant of body weight in middle-aged males.
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Adiponectin gene ADIPOQ SNP associations with serum adiponectin in two female populations and effects of SNPs on promoter activity
Theodosios Kyriakou,Laura J. Collins,Nicola J. Spencer-Jones,Claire Malcolm,Xiaoling Wang,Harold Snieder,Ramasamyiyer Swaminathan,Keith Burling,Deborah J. Hart,Tim D. Spector,Sandra D. O'Dell +10 more
TL;DR: Eight tagging single nucleotide polymorphisms in the ADIPOQ gene and promoter were selected, and association with serum adiponectin was tested, in two independent samples of Caucasian women.
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Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement
Maryam Al-Hilal,Aseel AlSaleh,Zoitsa Maniou,Fiona Lewis,Wendy L. Hall,Thomas A. B. Sanders,Sandra D. O'Dell +6 more
TL;DR: Different sites at the FADS1-FADS2 locus appear to influence D5D and D6D activity, and rs174537 genotype interacts with dietary EPA+DHA to modulate D5d.
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Effect of high-fat feeding on expression of genes controlling availability of dopamine in mouse hypothalamus.
Alex K. Lee,Marjan Mojtahed-Jaberi,Theodosios Kyriakou,Estibaliz Aldecoa-Otalora Astarloa,Matthew Arno,Nichola J. Marshall,Susan D. Brain,Sandra D. O'Dell +7 more
TL;DR: In this paper, the hypothalamic centers integrate external signals of nutrient availability and energy status and initiate responses to maintain homeostasis, and quantifying changes in hypothalamic gene expression in the presence of nutrient excess may identify novel responsive elements.