S
Sandra Guaita-Esteruelas
Researcher at Carlos III Health Institute
Publications - 19
Citations - 485
Sandra Guaita-Esteruelas is an academic researcher from Carlos III Health Institute. The author has contributed to research in topics: Adipose tissue & Fatty acid-binding protein. The author has an hindex of 11, co-authored 19 publications receiving 348 citations.
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Journal ArticleDOI
Exogenous FABP4 increases breast cancer cell proliferation and activates the expression of fatty acid transport proteins
Sandra Guaita-Esteruelas,Alba Bosquet,Paula Saavedra,Josep Gumà,Josefa Girona,Eric Lam,Kepa Amillano,Joan Borràs,Lluís Masana +8 more
TL;DR: It is shown that eFABP4 plays a key role in tumor proliferation and activates the expression of fatty acid transport proteins in MCF‐7 breast cancer cells.
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The peritumoural adipose tissue microenvironment and cancer. The roles of fatty acid binding protein 4 and fatty acid binding protein 5.
TL;DR: The role of the peritumoural adipose tissue and the related adipokines FABp4 and FABP5 in cancer initiation and progression and the possible pathways implicated in these processes are discussed.
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Clinical and pathophysiological evidence supporting the safety of extremely low LDL levels—The zero-LDL hypothesis
Luis Masana,Josefa Girona,Daiana Ibarretxe,Ricardo Rodríguez-Calvo,Roser Rosales,Joan-Carles Vallvé,Cèlia Rodríguez-Borjabad,Montserrat Guardiola,Marina Rodríguez,Sandra Guaita-Esteruelas,Iris Oliva,Neus Martínez-Micaelo,Mercedes Heras,Raimon Ferré,Josep Ribalta,Núria Plana +15 more
TL;DR: It is suggested that extremely low LDL-C levels due to increased LDLR activity may be a surrogate of adequate LDL-LDLR pathway function, which is the main mechanism for removal of cholesterol from the body.
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FABP4 inhibitor BMS309403 decreases saturated-fatty-acid-induced endoplasmic reticulum stress-associated inflammation in skeletal muscle by reducing p38 MAPK activation.
Alba Bosquet,Josefa Girona,Sandra Guaita-Esteruelas,Mercedes Heras,Paula Saavedra-García,Neus Martínez-Micaelo,Lluís Masana,Ricardo Rodríguez-Calvo +7 more
TL;DR: Findings indicate that FABP4 inhibitor BMS309403 reduces fatty acid-induced ER stress-associated inflammation in skeletal muscle by reducing p38 MAPK activation.
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The Circulating GRP78/BiP Is a Marker of Metabolic Diseases and Atherosclerosis: Bringing Endoplasmic Reticulum Stress into the Clinical Scenario.
Josefa Girona,Cèlia Rodríguez-Borjabad,Daiana Ibarretxe,Joan-Carles Vallvé,Raimon Ferré,Mercedes Heras,Ricardo Rodríguez-Calvo,Sandra Guaita-Esteruelas,Neus Martínez-Micaelo,Núria Plana,Lluís Masana +10 more
TL;DR: GRP78/BiP plasma concentrations are increased in patients with both metabolic derangements and subclinical atherosclerosis, suggesting that this protein could be a useful marker of metabolic and cardiovascular risk.