S
Sandra R. Georgetti
Researcher at Universidade Estadual de Londrina
Publications - 71
Citations - 2852
Sandra R. Georgetti is an academic researcher from Universidade Estadual de Londrina. The author has contributed to research in topics: Oxidative stress & Antioxidant. The author has an hindex of 26, co-authored 65 publications receiving 2300 citations. Previous affiliations of Sandra R. Georgetti include University of São Paulo.
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Protective effect of topical formulations containing quercetin against UVB-induced oxidative stress in hairless mice.
Rubia Casagrande,Sandra R. Georgetti,Waldiceu A. Verri,Daniel Junqueira Dorta,Antonio Cardozo dos Santos,Maria José Vieira Fonseca +5 more
TL;DR: This is the first study to demonstrate the effectiveness of topical formulations containing quercetin to inhibit the UVB irradiation-induced skin damages, and suggests the possible usefulness of topical formulated with quercETin to prevent UVB radiation skin damages.
Journal ArticleDOI
Quercetin-Loaded Microcapsules Ameliorate Experimental Colitis in Mice by Anti-inflammatory and Antioxidant Mechanisms
Carla F.S. Guazelli,Victor Fattori,Barbara B. Colombo,Sandra R. Georgetti,Fabiana T. M. C. Vicentini,Rubia Casagrande,Marcela M. Baracat,Waldiceu A. Verri +7 more
TL;DR: Preclinical data indicate that pectin/casein polymer microcapsules loaded with 1 improved the anti-inflammatory and antioxidant effects of 1 compared to the nonencapsulated drug, and quercetin seems to be a promising active molecule in inflammatory bowel disease if provided with adequate controlled release.
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Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice.
Cássia Calixto-Campos,Thacyana T. Carvalho,Miriam S. N. Hohmann,Felipe A. Pinho-Ribeiro,Victor Fattori,Marília F. Manchope,Ana C. Zarpelon,Marcela M. Baracat,Sandra R. Georgetti,Rubia Casagrande,Waldiceu A. Verri +10 more
TL;DR: The present study demonstrated 1 presents analgesic and anti-inflammatory effects in a wide range of murine inflammation models, and its mechanisms of action involves antioxidant effects and NFκB-related inhibition of pro-inflammatory cytokine production.
Journal ArticleDOI
Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production.
Daniel A. Valério,Sandra R. Georgetti,Danilo A. Magro,Rubia Casagrande,Thiago M. Cunha,Fabiana T. M. C. Vicentini,Silvio M. Vieira,Maria José Vieira Fonseca,Sérgio Henrique Ferreira,Fernando Q. Cunha,Waldiceu A. Verri +10 more
TL;DR: Quercetin (1) is known to have both antioxidant and antinociceptive effects as discussed by the authors, however, the mechanism involved in its antineuropathic effect is not fully elucidated.
Journal ArticleDOI
Spray drying of the soybean extract: Effects on chemical properties and antioxidant activity
Sandra R. Georgetti,Rubia Casagrande,Claudia R. F. Souza,Wanderley Pereira de Oliveira,Maria José Vieira Fonseca +4 more
TL;DR: In this article, the authors evaluated the effects of spray drying on the chemical and biological properties of soybean extract and found that the inlet gas temperature showed significant effect on the total polyphenol, protein and genistein contents of the dried extracts.