S
Sandy L. Nguyen
Researcher at Northwestern University
Publications - 22
Citations - 1074
Sandy L. Nguyen is an academic researcher from Northwestern University. The author has contributed to research in topics: Melanoma & Semiconductor. The author has an hindex of 14, co-authored 22 publications receiving 1017 citations. Previous affiliations of Sandy L. Nguyen include University of California, Los Angeles & Northwest University (United States).
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Journal ArticleDOI
Predictive Utility of Circulating Methylated DNA in Serum of Melanoma Patients Receiving Biochemotherapy
Takuji Mori,Steven J. O'Day,Naoyuki Umetani,Steve R. Martinez,Minoru Kitago,Kazuo Koyanagi,Christine Kuo,Teh Ling Takeshima,Robert Milford,He-Jing Wang,Vu D. Vu,Sandy L. Nguyen,Dave S.B. Hoon +12 more
TL;DR: In this article, the authors hypothesized that methylation of tumor-related genes detected in serum DNA could predict disease outcome and therapeutic response in patients receiving concurrent biochemotherapy (BC) for metastatic melanoma.
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Activation of Toll-like receptors 2, 3, and 4 on human melanoma cells induces inflammatory factors.
Yasufumi Goto,Takaaki Arigami,Minoru Kitago,Sandy L. Nguyen,Norihiko Narita,Soldano Ferrone,Donald L. Morton,Reiko F. Irie,Dave S.B. Hoon +8 more
TL;DR: These studies show expression and functional activity of specific TLRs on melanoma cells and as potential therapeutic targets to control tumor progression.
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Preparation and properties of metallic, superhard rhenium diboride crystals.
Jonathan B. Levine,Sandy L. Nguyen,Haider I. Rasool,Jeffrey Wright,Stuart Brown,Richard B. Kaner +5 more
TL;DR: Thermogravimetric analysis indicates that the crystals are stable in air up to 1000 degrees C due to the formation of a protective boron oxide coating and four-probe electrical resistivity measurements demonstrate that ReB(2) is the hardest material known to exhibit metallic behavior.
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Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors.
Eiji Sunami,Masaru Shinozaki,Myung-Shin Sim,Sandy L. Nguyen,Anh-Thu Vu,Armando E. Giuliano,Dave S.B. Hoon +6 more
TL;DR: Significant differences in tumor-related gene methylation patterns relevant to ER and HER2/neu status of breast tumors are demonstrated and may be of significance in the assessment of targeted therapy resistance related to ER-positive and ER-negative status in breast cancer patients.
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Estrogen receptor-α methylation predicts melanoma progression
Takuji Mori,Steve R. Martinez,Steven J. O'Day,Donald L. Morton,Naoyuki Umetani,Minoru Kitago,Atsushi Tanemura,Sandy L. Nguyen,Andy N. Tran,He-Jing Wang,Dave S.B. Hoon +10 more
TL;DR: Serum methylated ER-α is a significant factor in melanoma progression and was the only factor predicting progression-free and overall survival in biochemotherapy patients and sera is an unfavorable prognostic factor.