Sang Yong Song

TL;DR: Compared the clinical characteristics of two GBM patient groups divided according to CD133-positive cell ratios, the results suggest thatCD133-negative cells of GBMs also possess tumor-initiating potential, which is indicative of complexity in the identification of cancer cells for therapeutic targeting.

TL;DR: In this paper, the IDH1 codon 132 mutations were found in glioblastoma multiforme (GBM) and other gliomas, but none in other cancers.

TL;DR: Despite the infrequent incidence of the IDH1 mutations in prostate cancers and B‐ALL, mutated IDH 1 could be therapeutically targeted in these cancers and in glial tumors with the IDh1 mutations.

TL;DR: The data indicate that frameshift mutations in ATG genes with mononucleotide repeats are common in gastric and colorectal carcinomas with MSI‐H, and suggest that these mutations may contribute to cancer development by deregulating the autophagy process.

TL;DR: The present study suggests that tumor-specific methylation of APC, MGMT, RASSF2A, and Wif-1 genes might be a valuable biomarker in plasma for the early detection of colorectal cancer.