S
Sanne Verbruggen
Researcher at Maastricht University
Publications - 21
Citations - 1100
Sanne Verbruggen is an academic researcher from Maastricht University. The author has contributed to research in topics: Notch signaling pathway & Angiogenesis. The author has an hindex of 9, co-authored 20 publications receiving 784 citations.
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Journal ArticleDOI
Anti-inflammatory M2, but not pro-inflammatory M1 macrophages promote angiogenesis in vivo
Nadine Jetten,Sanne Verbruggen,Marion J.J. Gijbels,Mark J. Post,Menno P.J. de Winther,Marjo M. P. C. Donners +5 more
TL;DR: Results indicate that macrophages polarized towards an M2 phenotype have a higher angiogenic potential compared to other subsets, and propose FGF signaling for M2a- and PlGF signalingfor M2c-induced angiogenesis as possible working mechanisms.
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Alternatives for large-scale production of cultured beef: A review
TL;DR: It is anticipated that the optimization of large-scale cell culture as performed for other stem cells can be translated into successful protocols for bovine satellite cells resulting in resource and cost efficient cultured beef.
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Bovine myoblast cell production in a microcarriers-based system
TL;DR: This results provide valuable data to further develop and scale-up the production of bovine myoblasts as a prerequisite for efficient and cost-effective development of cultured meat.
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Feed-forward Signaling by Membrane-bound Ligand Receptor Circuit THE CASE OF NOTCH DELTA-LIKE 4 LIGAND IN ENDOTHELIAL CELLS
Vincenza Caolo,Nynke M. S. van den Akker,Sanne Verbruggen,Marjo M. P. C. Donners,Geertje Swennen,Henny Schulten,Johannes Waltenberger,Mark J. Post,Daniel G. M. Molin +8 more
TL;DR: Evidence is provided for a mechanism by which VEGF or ligand-induced NOTCH signaling up-regulates DLL4 through a positive feed-forward mechanism that could propagate its own expression and enable synchronization of NOTCH expression and signaling between ECs.
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CXCL1 promotes arteriogenesis through enhanced monocyte recruitment into the peri-collateral space
Mark H. M. Vries,Allard Wagenaar,Sanne Verbruggen,Daniel G. M. Molin,Ingrid Dijkgraaf,Tilman H. Hackeng,Mark J. Post +6 more
TL;DR: CXCL1 presented on the luminal endothelial surface leads to an increase in the number of peri-collateral macrophages, thus improving the arteriogenic response after arterial ligation.