S
Santiago Garcia-Vallvé
Researcher at Rovira i Virgili University
Publications - 64
Citations - 4670
Santiago Garcia-Vallvé is an academic researcher from Rovira i Virgili University. The author has contributed to research in topics: Genome & Virtual screening. The author has an hindex of 27, co-authored 60 publications receiving 3853 citations.
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OPTIMIZER: a web server for optimizing the codon usage of DNA sequences
TL;DR: One of the main features of OPTIMIZER is that it makes it possible to optimize a DNA sequence using pre-computed codon usage tables from a predicted group of highly expressed genes from more than 150 prokaryotic species under strong translational selection.
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Molecular fingerprint similarity search in virtual screening.
Adrià Cereto-Massagué,María José Ojeda,Cristina Valls,Miquel Mulero,Santiago Garcia-Vallvé,Gerard Pujadas +5 more
TL;DR: This review focuses on commonly used fingerprint algorithms, their usage in virtual screening, and the software packages and online tools that provide these algorithms.
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CAIcal: A combined set of tools to assess codon usage adaptation
TL;DR: The CAIcal server provides a complete set of tools to assess codon usage adaptation and to help in genome annotation, including the automated calculation of CAI and its expected value.
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Horizontal gene transfer in bacterial and archaeal complete genomes.
TL;DR: A statistical procedure for predicting whether genes of a complete genome have been acquired by horizontal gene transfer, based on the analysis of G+C contents, codon usage, amino acid usage, and gene position, found that informational genes were less likely to be transferred than operational genes.
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Inhibition of Angiotensin-Converting Enzyme Activity by Flavonoids: Structure-Activity Relationship Studies
Ligia Guerrero,Julián Castillo,Mar Quiñones,Santiago Garcia-Vallvé,Lluís Arola,Gerard Pujadas,Begoña Muguerza +6 more
TL;DR: The results suggest that flavonoids are an excellent source of functional antihypertensive products and the structure-activity relationship studies show that the combination of sub-structures on the flavonoid skeleton that increase ACEI activity is made up of the catechol group in the B-ring and the cetone group in C4 at the C-ring.