S
Sara A. Currie
Researcher at Merck & Co.
Publications - 13
Citations - 1798
Sara A. Currie is an academic researcher from Merck & Co.. The author has contributed to research in topics: Streptomyces & Antibacterial agent. The author has an hindex of 9, co-authored 13 publications receiving 1711 citations.
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Journal ArticleDOI
Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation
Richard W. Burg,Brinton M. Miller,E.E. Baker,Jerome Birnbaum,Sara A. Currie,R Hartman,Yulin Kong,Richard L. Monaghan,G Olson,Irving Putter,J B Tunac,Hyman Wallick,Edward O. Stapley,R Oiwa,Satoshi Omura +14 more
TL;DR: The avermectins are a complex of chemically related agents which exhibit extraordinarily potent anthelmintic activity and are produced by a novel species of actinomycete, NRRL 8165, which is named Streptomyces avermitilis.
Journal ArticleDOI
Thienamycin, a new beta-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties.
Jean S. Kahan,Frederick M. Kahan,Robert T. Goegelman,Sara A. Currie,M. Jackson,Edward O. Stapley,Thomas W. Miller,Miller Ak,David Hendlin,Sagrario Mochales,Sebastian Hernandez,H. B. Woodruff,Jerome Birnbaum +12 more
TL;DR: A new beta-lactam antibiotic, named thienamycin, was discovered in culture broths of Streptomyces MA4297, and subsequently determined to be a hitherto unrecognized species, is designated StrePTomyces cattleya (NRRL 8057).
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Cephamycins, a New Family of β-Lactam Antibiotics I. Production by Actinomycetes, Including Streptomyces lactamdurans sp. n
Edward O. Stapley,M. Jackson,Sebastian Hernandez,Sheldon B. Zimmerman,Sara A. Currie,Sagrario Mochales,Mata Justo M,H. B. Woodruff,David Hendlin +8 more
TL;DR: A number of actinomycetes isolated from soil were found to produce one or more members of a new family of antibiotics, the cephamycins, which are structurally related to cephalosporin C.
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Difficidin and oxydifficidin: novel broad spectrum antibacterial antibiotics produced by Bacillus subtilis. I: Production, taxonomy and antibacterial activity
Sheldon B. Zimmerman,Cheryl D. Schwartz,Richard L. Monaghan,Barbara A. Pelak,Barbara Weissberger,Evemarie C. Gilfillan,Sagrario Mochales,Sebastian Hernandez,Sara A. Currie,Enrique Tejera,Edward O. Stapley +10 more
TL;DR: Two novel macrocyclic polyene lactone phosphate esters were discovered in fermentation broths of each of two strains of Bacillus subtilis and each showed a broad spectrum of activity against aerobic and anaerobic bacteria.
Journal ArticleDOI
L-156,602, a C5a antagonist with a novel cyclic hexadepsipeptide structure from Streptomyces sp. MA6348. Fermentation, isolation and structure determination.
Otto D. Hensens,Robert P. Borris,Lawrence R. Koupal,Charles G. Caldwell,Sara A. Currie,Akber A. Haidri,Carl F. Homnick,Susan S. Honeycutt,Susan M. Lindenmayer,Cheryl D. Schwartz,Barbara Weissberger,H. B. Woodruff,Deborah L. Zink,Lauretta Zitano,Jill M. Fieldhouse,Thomas E. Rollins,Martin S. Springer,James P. Springer +17 more