S
Sara C. París
Researcher at University of Antioquia
Publications - 22
Citations - 875
Sara C. París is an academic researcher from University of Antioquia. The author has contributed to research in topics: Mycobacterium tuberculosis & Tuberculosis. The author has an hindex of 14, co-authored 22 publications receiving 838 citations.
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Journal ArticleDOI
Cytokine gene polymorphisms in Colombian patients with different clinical presentations of tuberculosis
TL;DR: Gene polymorphisms associated with cytokine production may be associated with clinical presentations of TB, and results suggest that IL-10 low-producer polymorphism and IFN-gamma high-produce polymorphism are associated with pleural TB.
Journal ArticleDOI
Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis
Nancy D. Marin,Sara C. París,Viviana Vélez,Carlos del Valle Rojas,Mauricio Rojas,Luis F. García +5 more
TL;DR: Results suggest that during active tuberculosis Tregs inhibit protective Th1 responses, but not the proinflammatory Th17 responses, facilitating mycobacterial replication and tissue damage.
Journal ArticleDOI
IFNγ Response to Mycobacterium tuberculosis, Risk of Infection and Disease in Household Contacts of Tuberculosis Patients in Colombia
Helena del Corral,Sara C. París,Nancy D. Marin,Diana Marín,Lucelly López,Hanna Marisol Henao,Teresita Martínez,Liliana Villa,Luis F. Barrera,Blanca L. Ortiz,María Elena Heras–Ramírez,Carlos Montes,María C. Oquendo,Lisandra M. Arango,Felipe Riaño,Carlos Aguirre,Alberto Bustamante,John T. Belisle,Karen M. Dobos,Gloria Isabel Mejía,M.R. Giraldo,Patrick J. Brennan,Jaime Robledo,María Patricia Arbeláez,Carlos del Valle Rojas,Luis F. García +25 more
TL;DR: The high tuberculosis incidence amongst children supports administration of chemoprohylaxis to child contacts regardless of BCG vaccination and a significant trend for tuberculosis development amongst high HHC IFNγ producers was observed.
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Inhibition of Virulent Mycobacterium tuberculosis by Bcgr and Bcgs Macrophages Correlates with Nitric Oxide Production
Mauricio A. Arias,Mauricio Rojas,Jovanny Zabaleta,Jaime I. Rodríguez,Sara C. París,Luis F. Barrera,Luis F. García +6 more
TL;DR: The Nramp1 gene controls macrophage resistance or susceptibility to several intracellular microorganisms; however, there is conflicting evidence regarding its role during infection with virulent Mycobacterium tuberculosis.
Journal ArticleDOI
Functional and phenotypic changes in monocytes from patients with tuberculosis are reversed with treatment.
María Dulfary Sánchez,Yoenis García,Carlos Montes,Sara C. París,Mauricio Rojas,Luis F. Barrera,Mauricio A. Arias,Luis F. García +7 more
TL;DR: Restoration of monocyte alterations during anti-TB treatment suggests that such alterations may be caused by the high M. tuberculosis load present during active disease.