S
Sara Rurgo
Researcher at University of Naples Federico II
Publications - 2
Citations - 40
Sara Rurgo is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Proinflammatory cytokine & Receptor. The author has an hindex of 1, co-authored 2 publications receiving 1 citations.
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Cannabidiol inhibits SARS-Cov-2 spike (S) protein-induced cytotoxicity and inflammation through a PPARγ-dependent TLR4/NLRP3/Caspase-1 signaling suppression in Caco-2 cell line.
Chiara Corpetti,Alessandro Del Re,Luisa Seguella,Luisa Seguella,Irene Palenca,Sara Rurgo,Barbara De Conno,Marcella Pesce,Giovanni Sarnelli,Giuseppe Esposito +9 more
TL;DR: In this paper, the in vitro PPAR-I³-dependent efficacy of CBD (10-9 -10-7 ǫ ) in preventing epithelial damage and hyperinflammatory response triggered by SARS-CoV-2 spike protein (SP) in a Caco-2 cells.
Journal ArticleDOI
Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages.
Alessandro Del Re,Chiara Corpetti,Marcella Pesce,Luisa Seguella,Luca Steardo,Irene Palenca,Sara Rurgo,Barbara De Conno,Giovanni Sarnelli,Giuseppe Esposito +9 more
TL;DR: In this article, the anti-inflammatory and immunomodulatory activity of ultramicronized palmitoylethanolamide ( um)-PEA, both alone and in the presence of specific peroxisome proliferator-activated receptor alpha (PPAR-α) antagonist MK886, in primary cultures of murine alveolar macrophages exposed to SARS-CoV-2 spike glycoprotein (SP).