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Sarah A. Field
Researcher at Southampton General Hospital
Publications - 3
Citations - 572
Sarah A. Field is an academic researcher from Southampton General Hospital. The author has contributed to research in topics: Immunotoxin & Cytotoxic T cell. The author has an hindex of 2, co-authored 3 publications receiving 504 citations.
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Journal ArticleDOI
Defective epithelial barrier function in asthma.
Chang Xiao,Sarah M. Puddicombe,Sarah A. Field,Joel Haywood,Victoria Broughton-Head,Ilaria Puxeddu,Hans Michael Haitchi,Elizabeth Vernon-Wilson,David Sammut,Nicole Bedke,Catherine Cremin,Jody Sones,Ratko Djukanovic,Peter H. Howarth,Jane E. Collins,Stephen T. Holgate,Phillip Monk,Donna E. Davies +17 more
TL;DR: The results show that the bronchial epithelial barrier in asthma is compromised, which may facilitate the passage of allergens and other agents into the airway tissue, leading to immune activation and may thus contribute to the end organ expression of asthma.
Journal ArticleDOI
The anti-CD20 antibody rituximab augments the immunospecific therapeutic effectiveness of an anti-CD19 immunotoxin directed against human B-cell lymphoma
David J. Flavell,Sarah L. Warnes,Christine J. Bryson,Sarah A. Field,A Noss,Graham Packham,Sopsamorn U. Flavell +6 more
TL;DR: A clear therapeutic advantage from using rituximab to immunospecifically augment immunotoxin cytotoxicity warranting further investigation is shown.