D
David Sammut
Researcher at University of Southampton
Publications - 13
Citations - 1217
David Sammut is an academic researcher from University of Southampton. The author has contributed to research in topics: Receptor & Interferon. The author has an hindex of 9, co-authored 11 publications receiving 1018 citations. Previous affiliations of David Sammut include Wellcome Trust & Southampton General Hospital.
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Journal ArticleDOI
Defective epithelial barrier function in asthma.
Chang Xiao,Sarah M. Puddicombe,Sarah A. Field,Joel Haywood,Victoria Broughton-Head,Ilaria Puxeddu,Hans Michael Haitchi,Elizabeth Vernon-Wilson,David Sammut,Nicole Bedke,Catherine Cremin,Jody Sones,Ratko Djukanovic,Peter H. Howarth,Jane E. Collins,Stephen T. Holgate,Phillip Monk,Donna E. Davies +17 more
TL;DR: The results show that the bronchial epithelial barrier in asthma is compromised, which may facilitate the passage of allergens and other agents into the airway tissue, leading to immune activation and may thus contribute to the end organ expression of asthma.
Journal ArticleDOI
Invariant Natural Killer T Cells in Asthma and Chronic Obstructive Pulmonary Disease
Pandurangan Vijayanand,Grégory Seumois,Chris Pickard,Robert M. Powell,Gilbert Angco,David Sammut,Stephan D. Gadola,Peter S. Friedmann,Ratko Djukanovic +8 more
TL;DR: Investigating the frequency of invariant natural killer T cells in the airways of subjects with mild or moderately severe asthma and whether an increased number of these cells is a feature of chronic obstructive pulmonary disease (COPD) found them in low numbers.
Journal ArticleDOI
Double-stranded RNA induces disproportionate expression of thymic stromal lymphopoietin versus interferon-beta in bronchial epithelial cells from donors with asthma.
Lena Uller,Marina S. Leino,Nicole Bedke,David Sammut,Ben Green,Laurie Lau,Peter H. Howarth,Stephen T. Holgate,Donna E. Davies +8 more
TL;DR: BECs from subjects with asthma are biased towards higher TSLP and lower IFNβ production in response to dsRNA, suggesting that viral infection in asthma may lead to an altered mediator profile that biases towards a Th2 immune response.
Journal ArticleDOI
Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis
Obbina Abani,Ali Abbas,Fatima Abbas,Joshua Abbas,Kasim Abbas,Mustafa Abbas,Sadia Abbasi,Hakam Abbass,Alfie Abbott,Alison Abbott,Nabeel Abdallah,Ammari Abdelaziz,Ashraf Omar Abdelaziz,Mohamed Rabei Abdelfattah,Bushra Abdelqader,Audrey Abdul,Basir Abdul,Siddiqui Abdul,A. Rasheed,Ajibode Abdulakeem,Rezan Abdul-Kadir,Abdullah Abdullah,Abdulfatahi Abdulmumeen,Rasheed Abdul-Raheem,Niyaz Abdulshukkoor,Kula Abdusamad,Y Abed El Khaleq,Mai Abedalla,Abeer Ul Amna,Lynn Abel,Katrina Abernethy,Movin Abeywickrema,C. Abhinaya,Affyarsyah Abidin,Adebanke Aboaba,Abigail Aboagye-Odei,Heba Aboelela,Hani Abo-Leyah,Karim Abouelela,Ahmed Abou-Haggar,Mahmoud Ahmed Abouibrahim,Ahmed O.S. Abousamra,M. Abouzaid,Miriam Abraham,T Augustin Abraham,A. Abraheem,Judith Abrams,Rebecca Abrams,Hyacinth-John Abu,A. Abu-Arafeh,Syed Mohamed Abubacker,Akata Abung,Yousuf Abusamra,Yaa Aceampong,Amaka Achara,Devikumar U. Acharya,Prince Acheampong,S. Acheampong,Joan Acheson,Shiella Achieng,A Acosta,Rebecca Acquah,Catherine Acton,Jacqueline Adabie-Ankrah,Paul C. Adair,F. Adam,Matthew Ayamba Adam,Huzaifa Adamali,Marta Adamczyk,Carol Adams,Charlotte Adams,Daniel Adams,Kate Adams,Laura Adams,Nikki Adams,Richard Adams,Tim Adams,Laura Adamu-Ikeme,Krishma Adatia,K Adcock,A. Addo,Oluwatobi Adeagbo,A. Adebiyi,O. Adedeji,Y A Adegeye,K Adegoke,Vicki Adell,Sherna F Adenwalla,Femi W Adeoye,Oluwasegun A Adesemoye,Emmanuel O Adewunmi,Adedamola Adeyanju,Joyce Adeyemi,Tenifayo Adeyemo,Binay Adhikari,Rina Adhikary,Adhikarla Aditya,Gabriel L. Adkins,Adnan Adnan,John Aeron-Thomas,Deborah Jean Affleck,Carmel Afnan,Muhammad Afridi,Zainab Aftab,Meenakshi Agarwal,Rachel S. Agbeko,Christian Onuorah Agbo,Sunil K. Aggarwal,Arameh Aghababaie,Laura Aguilar Jimenez,Shafana Ahamed Sadiq,Mohamed Nazeer,Mohammad Ahmad,Syed Masroor Ahmad,Afshan Ashfaque Ahmed,Ashar E Ahmed,Asim Ahmed,B Ahmed,Bilal Ahmed,Forizuddin Ahmed,Hamze Ahmed,Hanad Ahmed,Irshad Ahmed,Khaled H. Ahmed.,Khalil Ahmed,Liban Ahmed,Mahin Gulzar Ahmed,Mariam Ahmed,M. S. Ahmed,Naseer Ahmed,Nausheen Ahmed,Osman Ahmed,R. Ahmed,Rawya Ahmed,Rizwan Ahmad,Saif Ahmed,Sammiya Ahmed,Sana Ahmed,Syed H. Ahmed,Roa Ahmed Ali,S. Ahmer,Augustine Ahonia,Chris B. Aiken,Dhiraj Ail,M. Ainsworth,Myriam Ait Aissa,Lindianne Aitken,Bini Ajay,Abdulakeem Ajibode,Ayesha Ajmi,Nasim Akhtar,N. Akhtar,Suha Akili,B. S. Akinbiyi,Oludoyinsola Akindolie,Yinka Akinfenwa,Olugbenga Akinkugbe,I.O. Akinpelu,Mohammad Wasim Akram,Olugbenro Aktinade,Uzayr Akudi,Ahmad Al Aaraj,Asma Al Balushi,Majd Al Dakhola,Aladdin Al Swaifi,Eslam Al-Abadi,Adegoke Alabi,Narendra Aladangady,Mohamed Alafifi,Ayaz S. Alam,Sajid Alam,A. Al-Asadi,Kyriaki S. Alatzoglou,Paul S. Albert,L. Albon,A. Alcala,Gemma Alcorn,Stephen Alcorn,A Rojas Aldana,D.K. Alderdice,Abdullah Aldesouki,Rayan Aldouri,Jonathan Aldridge,Nicolas Aldridge,Ram M Ale,Ana Maria Alegria,Alison Alexander,Courtney Alexander,J R Alexander,Peter D. Alexander,Julyan Al-fori,Laith Alghazawi,Osama Alhabsha,Bahij Al-Hakim,Rafil Alhameed,Mohammed Zuhair Khaleel Al-Hayali,Shams Al-Hity,Ali Hassan A Ali,Amanda Ali,Asad Ali,Fawzi Ali,Jawad Ali,Maria Ali,Mohamed Ali,Mohammadzadeh Ali,Muhammad Ali,Nayab Ali,Oudai Ali,Ramla Ali,Sakina Yousuf Ali,Syed Amer Ali,Emilio Aliberti,Jade Alin,A. Alina,Analyn Alipustain,Fine Aliyuda,Katrin Alizadeh,M. Al-Jibury,Saba Al-Juboori,Majid Al-Khalil,Abdullah Alkhudhayri,Moutaz Alkhusheh,F Allan,N D Allan,AL Allanson,Robert Allcock,Eireann Allen,J.Stewart Allen,Kerry B. Allen,Louise Allen,Poppy Allen,Rebecca Allen,Sharon S Allen,Simon Allen,Tania Allen,Abiola Alli,Kathryn Allison,Be Allman,Helen Allsop,Linda Allsop,David Allsup,Amal Fuad Almahroos,Hassan Al-Moasseb,Magda J Al-Obaidi,Lina Alomari,Akram Al-Rabahi,Bahar Al-Ramadhani,Zayneb Al-Saadi,Riyam Al-Sammarraie,Inji M. Alshaer,Rustam Al-Shahi Salman,Warkaq Al-Shamkhani,Fadi AlSheikh,Bashar Al-Sheklly,S Altaf,Amanda Alty,Mary Alvarez,Maria Alvarez Corral,Edward Alveyn,Maysaa Alzetani,S. Amamou,N. Amar,Sakkarai Ambalavanan,Robert Ambrogetti,Chris Ambrose,A. Ameen,Katharine Ames,Maria R. Amezaga,Allison Amin,Amina Amin,K. U. Amin,Syed Shahriar Amin,T. Amin,Badshah Amit,Amjad Farooq Amjad,Neelma Amjad,Victoria Amosun,Muhammad Amsal,Khaled Amsha,Pugh Amy,Ann Anada,Atul Anand,Samantha Anandappa,Satya D Anantapatnaikuni,Ellen J. Anderson,Julie Anderson,Laura C. Anderson,Marina E Anderson,Michelle Anderson,Nicola Elzabeth Anderson,Rachel Anderson,Rob Anderson,Rory G. Anderson,Samantha Anderson,Wendy Anderson,P. Andreou,Angela Andrews,Antonette Andrews,Jillian Laura Andrews,JoyAnn Andrews,Kanayochukwu Aneke,Andrew Ang,Wan Wei Ang,Tammy Angel,Aramburo Angela,Paola Angelini,Lazarus Anguvaa,Oleg Anichtchik,Millicent Anim-Somuah,Krishnan Aniruddhan,Jessica Annett,Louise Anning,Patrick Anstey,Rebekah M. Anstey,Alpha Anthony,Aaron Anthony-Pillai,Philip J. Antill,Zhelyazkova Antonina,V. Anu,M. Anwar,E. Apetri,A. Apostolopoulos,Sarah Appleby,D Appleyard,M. Aquino,B.D. Araba,Samuel Aransiola,M. Araujo,Ann G. Archer,Denise L Archer,Sammy L. Archer,Simon Archer,Daniele Arcoria,Christian Ardley,A. Arias,O. O. Aribike,Ryoki Arimoto,Charlotte Arkley,Charlotte N. Armah,Ilianna E Armata,Jennifer S. Armistead,A. Armitage,CJ Armstrong,N Armstrong,S Armstrong,Wendy Armstrong,Philippa Armtrong,Heike Arndt,Clare Arnison-Newgass,David T Arnold,R Arnold,Andrew Arnott,Dhawal Arora,K. Arora,Pardeep Kumar Arora,Rishi Arora,A Arter,Armena Arumaithurai,Ayush Arya,R. Arya,D. Asandei,Adeeba Asghar,Malik Muhammad Asghar,A. S. M. Ashab,C. Ashbrook-Raby,Helen L Ashby,John Ashcroft,Sam Ashcroft,Georgia Asher,Zakariya Ashfak,Ayesha Ashfaq,Abdul Ashish,D Ashley,Sally Ashman-Flavell,S Ashok,Abdolrahman Ashour,Muhammad Zubair Ashraf,Saima Ashraf,Mohammad B Ashraq,Deb Ashton,S. Ashton,Andrew Ashworth,Fiona Ashworth,Rebecca Ashworth,A. Aslam,Imran Aslam,Suhail Aslam,Laura Aslett,Harshini Asogan,Atif Asrar,Omar Al Assaf,R. Astin-Chamberlain,Deborah Athorne,Billi Atkins,Christopher Atkins,Stacey Atkins,John P. Atkinson,Vicki Atkinson,Abolaji Atomode,Brygitta Atraskiewicz,A. A. Attia,Eva C Attubato,Marie Attwood,P. Aubrey,Zoltan Auer,Avinash Aujayeb,Aye Chan Lwin Aung,Hnin Aung,Ko Ko Kyaw Aung,Kyaw Thu Aung,Nwe Nwe Aung,Yin Nwe Aung,Zaw Myo Aung,Emily B. Austin,Karen Austin,Abdusshakur Auwal,Malcolm Avari,Miriam Avery,Nicholas Aveyard,Joanne Avis,Georgina Aviss,Cristina Avram,Paula Avram,Abuzar Awadelkareem,G. Awadzi,Mahmoud Awaly,Atia Awan,Aszad Aya,Eman Ayaz,Amanda Ayers,Jawwad Azam,Ahmed Azeem,Azharuddin,Ammar Aziz,Ghazala Aziz,Imran Aziz,N. Aziz,Ali Azkoul,A. Shah,Giada Azzopardi,H. Azzoug,Fiyinfoluwa Babatunde,Melvin Babi,Babiker Mustafa Babiker,Gayna Babington,Matthew Babirecki,Marta Babores,Adetona O Babs-Osibodu,Sammy Bacciarelli,Roudi Bachar,Michel Bachour,Ginny Bacon,Jenny Louise Bacon,Bibi Badal,Mary B. Bader,Gurpreet R Badhan,Shreya Badhrinarayanan,Alice Baggaley,Amy V. Baggott,Graham Bagley,Dinesh Bagmane,Lynsey Bagshaw,Kasra Bahadori,Angela L. Bailey,James Bailey,K Bailey,Lindsey Bailey,Liz Bailey,Lucy A. Bailey,Mary A. Bailey,Morgan Bailey,Pippa Bailey,Sarah Bailey,Hamish Baillie,J Kenneth Baillie,Jennifer Bain,Vikram Bains,D. Baird,E.M. Baird,Kevin Baird,Susan Baird,Tracy Baird,Yolanda Baird,Aiysha Bajandouh,Daniel Claire Baker,Elizabeth Baker,Evelyn Baker,J. Baker,Josephine Baker,Kenneth Scott Baker,Mark S. Baker,Rebecca M. Baker,Terri Baker,Victoria Baker,H Bakere,Nawar Diar Bakerly,Michelle Baker-Moffatt,Ameet Bakhai,Nauman Bakhtiar,Panos Bakoulas,D. Bakthavatsalam,Niran Balachandran,Andrea Balan,P Balasingam,Theodosios Balaskas,Madhura Balasubramaniam,Nicola Balatoni,Alison Balcombe,Alexander J. Baldwin,Ashley Baldwin,C. E. Baldwin,Danielle Baldwin,Fiona Baldwin,Rebekah Baldwin-Jones,Nichola Bale,J. Balfour,M. Ball,Robert Ball,Kasia Ballard,I. M. Balluz,Craig Balmforth,Emese Balogh,Abeir Baltmr,A. Baluwala,Gabrielle Bambridge,Alasdair Bamford,Amy Bamford,Pete Bamford,Adefunke Bamgboye,Elizabeth Bancroft,Hollie Bancroft,Joyce Banda,Krishna Bandaru,Srini Bandi,Nageswar Bandla,Somaditya Bandyopadhyam,Amit Banerjee,Ritwik Banerjee,Omar Bani-Saad,Harrison S. Banks,Luke Banks,Paul Banks,C. Bann,H. Bannister,Oliver Bannister,Laura Banton,Tran Nguyen Bao,M. Baptist,T Baqai,Ananya M Baral,Desislava Baramova,Russell Barber,Emma Barbon,Mônica Barbosa,J Barbour,Alexander Barclay,Amanda Barclay,Claire Barclay,George Bardsley,Stephanie Bareford,S Bari,M.L. Barimbing,Amy Barker,Debbie Barker,Erandi Barker,Helen Barker,Joseph Barker,Len Barker,Lesley Barker,Oliver Barker,Kerry Barker-Williams,Sinha Barkha,J. R. Barla,Gavin Barlow,R. Barlow,Valérie G. Barlow,James R. Barnacle,A Barnard,Debi Barnes,N. Barnes,Rory Barnes,Terri Barnes,Calum Barnetson,A L Barnett,Ashton Barnett-Vanes,W C Barnsley,Andrew Barr,David A Barr,James Barr,C. Barr,N. R. Barratt,S. Barratt,M. Barrera,Amy Barrett,Fiona Barrett,Jessica Barrett,Susan Barrett,Esther W. Barrow,J. Bartholomew,Claire Bartlett,G Bartlett,James L. Bartlett,Louise E. Bartlett,Shauna Bartley,Sandra Bartolmeu-Pires,Anna D. Barton,Greg Barton,Jill Barton,Lorna L Barton,Rachael Barton,Rosaleen Baruah,S Baryschpolec,Hannah Bashir,A. Bashyal,Betsy Basker,Buddha Basnyat,Ayten Basoglu,Alexander Basran,J. Bassett,G. Bassett,Christopher Bassford,B Bassoy,V. Bastion,Anup Bastola,Anupam Basumatary,Precious Basvi,Vipula R. Bataduwaarachchi,Tristan Bate,Harry J Bateman,Kathryn M. Bateman,Vhairi M Bateman,Eleanor Joanne Wilson Bates,Hayley Bates,Michelle Bates,Simon R.G. Bates,Sally Batham,Ana Paula Batista,Amit Batla,Dushyant Batra,H. Batty,Thomas Batty,Alice M. Batty,Miranda L Baum,Rachel Baumber,C. Bautista,Fareha Najeeb Mohideen Bawa,Tanveer Bawa,Fatima S Bawani,Simon Bax,Matt Baxter,Nicola Baxter,Z. Baxter,Hannah K. Bayes,L. Bayo,Farid Bazari,Rohit Bazaz,A. Lutfi Ahmad Bazli,Laura Beacham,W I Beadles,Kirsten Beadon,Philip Beak,A. Beale,K K Beard,Jack Bearpark,A W Beasley,Sandee Beattie,Karen Beaumont,Dawn Beaumont-Jewell,Theresa Beaver,Sara Beavis,C. Raymond Beazley,Sarah W. Beck,Virginia Beckett,Rosie Beckitt,S. Beckley,Heidi Beddall,Seonaid Beddows,D.I. Beeby,Sophia Beeby,Gail Beech,M L Beecroft,N. Beer,Sally Beer,J M Beety,Gabriela Bega,A.J. Begg,S Begg,Sara Beghini,Ayesha Begum,S K Shabana Begum,Selina Begum,T. Behan,Roya Behrouzi,J. Beishon,C. Beith,James O. Belcher,H. Belfield,Katherine Belfield,Ajay P. Belgaumkar,D Bell,Gareth Bell,Gillian Bell,Jessica Bell,Lauren Bell,Louise Bell,Nichola Bell,P. Bell,Stephanie Bell,Jennifer Bellamu,Mary Bellamy,Tammy Bellamy,A. Bellini,Amanda Bellis,Fionn Bellis,Lesley Bendall,Naveena Benesh,Nicola Benetti,Leonie Benham,Guy Benison-Horner,Sarah Benkenstein,Tracey Benn,A. Bennett,Caroline Bennett,Denise Bennett,Gillian Bennett,Kaytie Bennett,Kristopher Bennett,Lorraine Bennett,Miriam R Bennett,S. Bennett,Karen Bennion,G. Benoy,Vivienne Benson,Andrew Bentley,James Richard Bentley,Ian Benton,Eva Beranova,Matthew Beresford,C J Bergin,Malin Bergstrom,Jolanta Bernatoniene,T J Berriman,Zoe Berry,F. Best,K. Best,Ans-Mari Bester,Yvonne Beuvink,E B Bevan,Sarah L Bevins,Thomas Bewick,Andrew Bexley,Sonay Beyatli,Fenella Beynon,Arjun Bhadi,Sanjay Bhagani,Shiv Bhakta,Rekha Bhalla,Khushpreet Bhandal,Kulbinder Bhandal,Ashwin Bhandari,Lilanath Bhandari,Sangam Bhandari,Jennifer Bhanich Supapol,Aashutosh Bhanot,Ravina Bhanot,Swati S. Bhasin,Abdul Rauf Bhat,Prashanth Bhat,Rahul Bhatnagar,Karan D. Bhatt,J. Bhayani,Deepika Bhojwani,Parminder Bhuie,Salim Bhuiyan,Anna C. Bibby,Fatima Bibi,Naheeda Bibi,Salma Bibi,Tihana Bicanic,Sally Bidgood,J. V. Bigg,Sarah J Biggs,A. Biju,Andras Bikov,Sophie A M Billingham,J. Billings,Alice Binns,Muhammad BinRofaie,Oliver J Bintcliffe,Catherine Elizabeth Birch,J. Birch,J. Birch,Kathryn Birchall,Sam Bird,Sumedha Bird,Sarah Bird,M. Birt,Claire Bishop,Kilanalei Bishop,Linda Bishop,Lisa Brenner Bishop,Karen Bisnauthsing,Nibedan Biswas,Sahar Biuk,Karen G. Blachford,Ethel Black,Helen Black,Karen M. Black,M. Black,Polly Black,Virginia H. Black,Hayley Blackgrove,Bethan Emma Blackledge,Joanne Blackler,S Blackley,Helen Blackman,C. R. Blackstock,Cameron J. Blair,Frances Blakemore,H Blamey,A. Bland,Sujata Blane,Simon Blankley,P. Blaxill,K. Blaylock,Jane M Blazeby,Natalie S Blencowe,Ben Bloom,John Bloomfield,Angela Bloss,Alex Blowers,Samuel Joseph Blows,H. P. Bloxham,Susan Blrd,Louise May Blundell,Andrew Blunsum,Mark Blunt,Tadhg J.G. Blunt,Ian Blyth,Kevin G. Blyth,Andrew Blythe,K. Blythe,Marilyn Boampoaa,Sarah Board,Boniface Bobie,Karen Bobruk,Pritesh N Bodalia,Neena Bodasing,Maria K. Bodén,Tanya Jayne Bodenham,Gabriele Boehmer,Marta Boffito,Katherine Bohanan,Kristyna Bohmova,Niamh Bohnacker,Sumit S Bokhandi,M. H. Bokhar,S.A. Bokhari,S. Hassan Akhtar Bokhari,Syed O Bokhari,Idan Bokobza,A. J. Boles,Clare Bolger,Charlotte Broegger Bond,Helen S. Bond,Stuart Bond,Thomas Bond,Alice Bone,Georgia Boniface,Lizzy Bonney,Lauren A Booker,S. Boot,Matthew Boothroyd,J. Borbone,Naomi Borman,Samantha Bosence,Kirsty Bostock,Neil Botting,Fiona E Bottrill,Hannah Bouattia,L. Bough,H. Boughton,Zoe Boult,T Boumrah,M. Bourke,Stephen Bourke,Michelle Bourne,Rachel Bousfield,Lucy Boustred,A. Bowes,Amy L. Bowes,Philip Bowker,T Bowker,Helen Bowler,Louise Bowman,Simon J. Bowman,Rachel Bowmer,Angela Bowring,Helen Samantha Bowyer,Aileen E. Boyd,Jenny Boyd,Laura Boyd,Nicola Boyer,N Boyle,P. Boyle,R. Boyle,L. O. Boyles,L. H. Brace,Abbey Bracken,Jodie Bradder,Clare Bradley,Pamela Bradley,Patrick H. Bradley,P. Bradley,J. Bradley-Potts,Lynne Bradshaw,Z. Bradshaw,Clare Brady,Rebecca Brady,Shirin Brady,Pedro Braga Sardo,Denise Braganza,M. E. Braithwaite,Susan Brammer,Marie E. Branch,Tom Brankin-Frisby,Jamie Brannigan,Sophie Brattan,F. Bray,Nancy Bray,M. Brazil,L. Brear,T. Brear,Stephen P. Brearey,L Bremner,Morwenna Brend,Carolin Bresges,Catherine Bressington,Giovanna Bretland,Chris Brewer,Michael Bridgett,Gavin Bridgwood,S.A. Brigham,John Bright,Christopher E. Brightling,Tracey Brigstock,L. Brimfield,Philip Brinksman,E Brinkworth,Robin Brittain-Long,Vianne Britten,Hannah Rose Britton,L. Broad,Sarah Broadhead,Rosie Broadhurst,Andrew J.M. Broadley,Mary K. Broadway,C Brockelsby,M.G.M. Brocken,Tomos Brockley,Mara Brodsky,Fiona Brogan,Liz Brohan,Felicity Brokke,J. B. Brolly,David Bromley,Hannah Brooke-Ball,Verity Brooker,Matthew J Brookes,Deirdre Brooking,Alison Brooks,Daniel Brooks,Jolene Brooks,Karen K. Brooks,Nicole D Brooks,Philip R. Brooks,Rachel Brooks,Samuel O. Brooks,Sophie V. Brooks,M. A. Broom,Natalie Broomhead,C R Broughton,N. W. Broughton,M. Brouns,Alison Brown,Ammani Brown,Andrew W. Brown,Ashley Brown,Caitlin C. Brown,Carl R. Brown,C.C. Brown,E. Brown,Heather J. Brown,Janet Brown,Joanne Brown,Louise Brown,Niall Brown,Nicola Brown,Pauline Brown,Richard H. Brown,Robert Brown,Steven R. Brown,Tom Brown,Brian Browne,Charlotte Browne,D Browne,Mitchell Browne,Steven Albert Brownlee,Alba Brraka,Johanna Bruce,M Bruce,Wojciech Brudlo,Andrei Brunchi,Nigel J. Brunskill,Alan P.T. Brunton,Margaret Brunton,Meera Bryant,Emma Bryden,Hannah Brzezicki,April Buazon,Maya H Buch,Ruaridh Buchan,D. Buche,Amanda Buck,Lisa Buck,Matthew Buckland,Clare Buckley,Laura Buckley,Philip Buckley,S. Buckley,Carol Buckman,Alex Budds,George Bugg,Ramadan Bujazia,Marwan Bukhari,Shan Bukhari,Richard Bulbulia,Alex Bull,Damian Bull,Kate Bull,R. Bull,Thomas Bull,Emily E. Bullock,Susie Bullock,Naomi S. Bulteel,Kasun Bumunarachchi,Roneleeh Bungue-Tuble,Oliver Burbidge,Caroline Burchett,D Burda,Christy Burden,Thomas G Burden,Mika Burgess,R Burgess,Sophia Burgess,Hasan Arda Burhan,Hannah Burke,Kerry Shannon Burke,Adrian Burman,Sarah Burnard,Carolyn. Burnett,Sharon Burnett,Amy Burns,C. Burns,James Burns,Karen Burns,Kiki Burns,Daniel Burrage,Kate Burrows,C. Burston,A. J. Burton,Ben J L Burton,Fiona M. Burton,Helen Brown Burton,Matthew J. Burton,Mannaria Butar butar,Deborah Butcher,Aaron Ross Butler,Emily Butler,J. Butler,Joanne Burke Butler,Joshua Kulmac Butler,Peter Butler,S Butler,Jenny Butler,Alina Butt,Massawer Butt,Muhammad Mohsin Butt,Caryl Butterworth,Nicola Butterworth-Cowin,Robert Buttery,T Buttle,H. Button,Daniel Buttress,Hannah Bye,Jean Byrne,Wendy Byrne,Victoria Byrne-Watts,Amanda Cabandugama,L. J. Cabrero,Simone Caddy,R. Cade,A.M. Cadwgan,Z. Cahilog,Ajeng Cahyareny,Donna Cairney,James Calderwood,Darren Caldow,Emily L Cale,Giorgio Calisti,Debbie Callaghan,Jennifer A. Callaghan,Claire Callens,Donald K. Mac Callum,C. Calver,Melissa Cambell-Kelly,Tracey Camburn,D. Richard Cameron,Eleanor Ruth Cameron,Fraser Cameron,S. Cameron,Christian F. Camm,R. Cammack,Alison M. Campbell,Amy F Campbell,Barbara Campbell,Bridget L. Campbell,Debbie Campbell,Helen Campbell,Hilary Campbell,Jonathan N Campbell,Karen K. Campbell,Marion Campbell,Mark Campbell,R. Joe Campbell,Robyn Campbell,W. G. Campbell,Quentin D. Campbell Hewson,Julie Camsooksai,Lisa Canclini,Shaula M Candido,J. Ralph Candlish,Cielito Caneja,A. Cann,J. P. le Cann,Ruby Cannan,Abigail R. Cannon,Emma Cannon,Michael David Cannon,P. Cannon,V. Cannons,Ebnier Canonizado,Jane Cantliff,Ben Caplin,Santino Capocci,Noemi Caponi,A. Capp,Richard Capstick,Thomas Capstick,Catalin Caraenache,Alan J. Card,Mary E Cardwell,Charles Carey,Rachel Carey,Simon Carley,Ffion Carlin,T. Carlin,Samantha J Carmichael,Margaret Carmody,Mandy Carnahan,Charlotte Caroline,Jodi Carpenter,S. Carr,Anna Carrasco,Zoe Carrington,Amy Carroll,Anne Corinne Carroll,Paul T. Carroll,Rachel Carson,Cindy Cart,Emma Carter,Jonathan Carter,Michael J. Carter,NaTasha Carter,P. Carter,Penny Carter,D B Cartwright,John Cartwright,Clare Carty,Lotoyah Carty,Jaime Carungcong,Charlotte E. Carver,Emma Carver,Rachel Carver,Susan Casey,Annie Cassells,Teresa Castiello,Gail Castle,Bridget Castles,Melanie Caswell,A. M. Catana,H Cate,A. C. Zborowski,S Cathcart,Katrina Cathie,Darwin Catibog,Christine Cole Catley,L. Catlow,Matthew Caudwell,Anna Cavazza,Ashleigh Cave,L. Cave,Simon Cavinato,Frianne Cawa,Kathleen M. Cawley,C. Caws,K. Cawthorne,Hankins Cendl,Hannah Century,J.O. Cernova,M.L. Cesay,Edward J. Cetti,S. Chabane,Manish Chablani,Cathleen Chabo,Cyril Jacob Chacko,David Chadwick,Julie Chadwick,Robert Ian Chadwick,Ela Chakkarapani,Arup Chakraborty,Mallinath Chakraborty,Mollika Chakravorty,Petya Chalakova,Bimal S. Chalise,James Chalmers,R Chalmers,G. V. Chamberlain,Sarah Chamberlain,Emma Chambers,John Chambers,Lucy Chambers,Naomi Chambers,Alex Chan,Carmen Chan,Cheuk Man Chan,Evelyn Chan,Jay Chan,Kawai Anita Chan,Kayen Chan,Kim Jong Chan,Ping Jung Chan,Xin Hui S Chan,Chris Chandler,Heidi Chandler,Kimberley Chandler,Stuart Chandler,Z. M. Chandler,Sumit Chandra,Navin Chandran,Badrinathan Chandrasekaran,Yvonne Chang,Grace Chaplin,Joseph B. 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Tadros,Amr Tageldin,Lucy Tague,Hasan Tahir,Muhammad Tahir,Michael Tai,Jennifer L. Tait,A.K. Takyi,Peter Talbot,Alison Smith,J Talbot-Ponsonby,Richard James Tallent,Bradley Tallon,Adrian Tan,Bee T T Tan,Hock Tan,Huey K Tan,Jenny Chern Nee Tan,J. S. Tan,Keith Tan,Wei Tan,Anand Tana,Alex R Tanner,C. Tanney,T. Tanqueray,Emma Tanton,Anita Tantri,Tm Tanzil-Al-Imran,H. Tarft,Priyal Taribagil,Obaid Tarin,Syed Fawad Tariq,David Tarpey,Esther Tarr,Lisa Tarrant,A Tasiou,Alex Tate,Margaret Tate,M. E. Tate,Paul Tate,Kate Tatham,Silvia Schaefer Tavares,V. Tavoukjian,Shao An Isaac Tay,Alexander Taylor,Beverley A. P. Taylor,Charles W. Taylor,Charlotte H. Taylor,D. Taylor,Elisabeth Taylor,Holly T. Taylor,Janet Taylor,Jennifer A. Taylor,Joanne Taylor,Julie Taylor,K. Taylor,Leanne Taylor,Margaret Taylor,Matthew Taylor,Melanie Anne Taylor,Natalie Taylor,Rachael M. Taylor,Rachel Marie Taylor,Samantha J. Taylor,Suzanne Taylor,Tracey Taylor,Vicky Taylor,Michelle Taylor-Siddons,Thomas Taynton,A. 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Zubikarai,Azam Zubir,N Zuhra,R Siti Zulaikha,Sabrina Zulfikar,Caroline K. Zullo,Ana Zuriaga-Alvaro +7885 more
TL;DR: In patients hospitalised with COVID-19, baricitinib significantly reduced the risk of death but the size of benefit was somewhat smaller than that suggested by previous trials.
Journal ArticleDOI
Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells.
Youwen Yang,Hans Michael Haitchi,Julie A. Cakebread,David Sammut,Anna Harvey,Robert M. Powell,John W. Holloway,Peter H. Howarth,Stephen T. Holgate,Donna E. Davies +9 more
TL;DR: The ADAM33 gene contains a regulatory CpG island within its promoter, the methylation status of which tightly controls its expression in a cell type-specific manner, and is a stable feature of airway epithelial cells, irrespective of disease.