S
Sarah Berhane
Researcher at University of Birmingham
Publications - 47
Citations - 4240
Sarah Berhane is an academic researcher from University of Birmingham. The author has contributed to research in topics: Hepatocellular carcinoma & Liver function. The author has an hindex of 17, co-authored 43 publications receiving 2519 citations. Previous affiliations of Sarah Berhane include University of Liverpool & Clatterbridge Cancer Centre NHS Foundation Trust.
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Journal ArticleDOI
Assessment of Liver Function in Patients With Hepatocellular Carcinoma: A New Evidence-Based Approach—The ALBI Grade
Philip J. Johnson,Sarah Berhane,Chiaki Kagebayashi,Shinji Satomura,M Teng,Helen L. Reeves,James O'Beirne,Richard Fox,Anna Skowronska,D. Palmer,Winnie Yeo,Frankie Mo,Paul B.S. Lai,Mercedes Iñarrairaegui,Stephen L. Chan,Bruno Sangro,Rebecca A. Miksad,Toshifumi Tada,Takashi Kumada,Hidenori Toyoda +19 more
TL;DR: The ALBI grade offers a simple, evidence-based, objective, and discriminatory method of assessing liver function in HCC that has been extensively tested in an international setting and eliminates the need for subjective variables such as ascites and encephalopathy, a requirement in the conventional C-P grade.
Journal ArticleDOI
Rapid, point-of-care antigen and molecular-based tests for diagnosis of SARS-CoV-2 infection.
Jacqueline Dinnes,Jacqueline Dinnes,Jonathan J Deeks,Ada Adriano,Sarah Berhane,Clare Davenport,Sabine Dittrich,Devy Emperador,Yemisi Takwoingi,Jane Cunningham,Sophie Beese,Janine Dretzke,Lavinia Ferrante di Ruffano,Isobel Marion Harris,Malcolm J Price,Sian Taylor-Phillips,Lotty Hooft,Mariska M.G. Leeflang,René Spijker,Ann Van den Bruel +19 more
TL;DR: Assessment of the diagnostic accuracy of point‐of‐care antigen and molecular‐based tests to determine if a person presenting in the community or in primary or secondary care has current SARS‐CoV‐2 infection found no studies at low risk of bias for all quality domains and concerns about applicability of results across all studies.
Journal ArticleDOI
Development of pre and post-operative models to predict early recurrence of hepatocellular carcinoma after surgical resection.
Anthony W.H. Chan,Jian-Hong Zhong,Sarah Berhane,Hidenori Toyoda,Alessandro Cucchetti,KeQing Shi,Toshifumi Tada,Charing C N Chong,Bang-De Xiang,Le-Qun Li,Paul B.S. Lai,Vincenzo Mazzaferro,Marta García-Fiñana,Masatoshi Kudo,Takashi Kumada,Sasan Roayaie,Philip J. Johnson +16 more
TL;DR: Large international study develops a statistical method that allows clinicians to estimate the risk of recurrence in an individual patient and shows that such models will be valuable in guiding surveillance follow-up and in the design of post-resection adjuvant therapy trials.
Journal ArticleDOI
Role of the GALAD and BALAD-2 Serologic Models in Diagnosis of Hepatocellular Carcinoma and Prediction of Survival in Patients
Sarah Berhane,Hidenori Toyoda,Toshifumi Tada,Takashi Kumada,Chiaki Kagebayashi,Shinji Satomura,Nora Schweitzer,Arndt Vogel,Michael P. Manns,Julia Benckert,Thomas Berg,Maria Ebker,Jan Best,Alexander Dechêne,Guido Gerken,Joerg F. Schlaak,Arndt Weinmann,Marcus A. Wörns,Peter R. Galle,Winnie Yeo,Frankie Mo,Stephen L. Chan,Helen L. Reeves,Trevor Cox,Philip J. Johnson,Philip J. Johnson +25 more
TL;DR: The performance of the GALAD and BALAD-2 models for the diagnosis of HCC and predicting patient survival, respectively are validated in an international cohort of patients and might be used in HCC surveillance and determination of patient prognosis.
Journal ArticleDOI
The Detection of Hepatocellular Carcinoma Using a Prospectively Developed and Validated Model Based on Serological Biomarkers
Philip J. Johnson,Sarah Pirrie,Trevor Cox,Sarah Berhane,M Teng,Daniel H. Palmer,Janet Morse,Diana Hull,G.L. Patman,Chiaki Kagebayashi,Syed A. Hussain,Janine Graham,Helen L. Reeves,Shinji Satomura +13 more
TL;DR: Evidence is provided that an entirely objective serum biomarker–based model may facilitate the detection and diagnosis of hepatocellular carcinoma and form the basis for a prospective study comparing this approach with the standard radiological approaches.