S
Sarah Reichardt
Publications - 4
Citations - 37
Sarah Reichardt is an academic researcher. The author has contributed to research in topics: Bacteroides thetaiotaomicron & RNA. The author has an hindex of 1, co-authored 2 publications receiving 22 citations.
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Journal ArticleDOI
A high-resolution transcriptome map identifies small RNA regulation of metabolism in the gut microbe Bacteroides thetaiotaomicron
TL;DR: The authors used differential RNA sequencing (dRNA-seq) to generate a single-nucleotide resolution transcriptome map of Bacteroides thetaiotaomicron grown under defined laboratory conditions.
Journal ArticleDOI
Comparative genomics provides structural and functional insights into Bacteroides RNA biology
Gianluca Prezza,Daniel Ryan,Gohar Mädler,Sarah Reichardt,Lars Barquist,Alexander J. Westermann +5 more
TL;DR: In this paper, a comparative genomics approach was used to investigate RNA biology in an understudied gut bacterium, using Bacteroides thetaiotaomicron as a representative microbiota member.
Posted ContentDOI
A CRISPR-based genetic screen in Bacteroides thetaiotaomicron reveals a small RNA modulator of bile susceptibility
TL;DR: In this article , the authors established CRISPR interference in the abundant microbiota member Bacteroides thetaiotaomicron for genome-wide sRNA screens by assessing the abundance of different protospacer-adjacent motifs and identifying the Prevotella bryantii B14 Cas12a as a suitable nuclease.
Posted ContentDOI
Improved RNA stability estimation through Bayesian modeling reveals most bacterial transcripts have sub-minute half-lives
Laura Jenniches,Charlotte Michaux,Sarah Reichardt,Jörg Vogel,Alexander J. Westermann,Lars Barquist +5 more
TL;DR: In this article , a hierarchical Bayesian model was developed to correct for confounding factors in rifampicin RNA stability assays and enables to identify differentially decaying transcripts transcriptome-wide.