Sarah Röhrig

TL;DR: In this article, a combination of T-DNA insertional mutants and targeted CRISPR/Cas mutagenesis was used to generate null mutants of the duplicated Arabidopsis transverse filament genes zyp1a and zyp 1b.

TL;DR: It is demonstrated that, in Arabidopsis thaliana, RMI2 is involved in the repair of aberrant replication intermediates in root meristems as well as in intrastrand crosslink repair, and loss of suppression of HR does not only lead to a destabilization of rDNA repeats but might be especially deleterious for tissues undergoing multiple cell divisions such as the male germline.

TL;DR: A homolog of the Fe-S cluster helicase FANCJ in the model plant Arabidopsis, AtFANCJB, is characterized and shown that it is involved in interstrand CL repair and involved in safeguarding rDNA stability in plants.

TL;DR: It is concluded that, as in fungi, AtHRQ1 has a conserved function in DNA excision repair and not only shares pathways with the Fanconi anemia repair factors, but in contrast to fungi also seems to act in a common pathway with postreplicative DNA repair.

TL;DR: It is concluded that the ZFD T1 is specifically required for targeting the topoisomerase activity to HJ like recombination intermediates to enable their processing in the case of an inactivated enzyme.