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Sarah T. Pendlebury

Researcher at University of Oxford

Publications -  146
Citations -  6531

Sarah T. Pendlebury is an academic researcher from University of Oxford. The author has contributed to research in topics: Stroke & Dementia. The author has an hindex of 34, co-authored 129 publications receiving 5153 citations. Previous affiliations of Sarah T. Pendlebury include University of Modena and Reggio Emilia & National Institute for Health Research.

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Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis.

TL;DR: The strong association of post-stroke dementia with multiple strokes and the prognostic value of other stroke characteristics highlight the central causal role of stroke itself as opposed to the underlying vascular risk factors and, thus, the likely effect of optimum acute stroke care and secondary prevention in reducing the burden of dementia.
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Underestimation of Cognitive Impairment by Mini-Mental State Examination Versus the Montreal Cognitive Assessment in Patients With Transient Ischemic Attack and Stroke A Population-Based Study

TL;DR: The MoCA picked up substantially more cognitive abnormalities after transient ischemic attack and stroke than the Mini-Mental State Examination, demonstrating deficits in executive function, attention, and delayed recall.
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MoCA, ACE-R, and MMSE Versus the National Institute of Neurological Disorders and Stroke–Canadian Stroke Network Vascular Cognitive Impairment Harmonization Standards Neuropsychological Battery After TIA and Stroke

TL;DR: The MoCA and ACE-R had good sensitivity and specificity for MCI defined using the Neurological Disorders and Stroke–Canadian Stroke Network Vascular Cognitive Impairment Battery ≥1 year after transient ischemic attack and stroke, whereas the MMSE showed a ceiling effect.
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Vascular Cognitive Impairment and Dementia: JACC Scientific Expert Panel.

TL;DR: A critical appraisal of the epidemiology, pathobiology, neuropathology, and neuroimaging of vascular cognitive impairment and dementia and of current diagnostic and therapeutic approaches is provided to shed light on new basic and clinical research avenues that may lead to mitigating one of the most devastating human conditions.
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The motor cortex shows adaptive functional changes to brain injury from multiple sclerosis.

TL;DR: It is demonstrated that cortical recruitment for simple finger movements can change both quantitatively and qualitatively in the SMCs of MS patients, suggesting that cortical reorganization or “unmasking” of latent pathways can contribute to functional recovery.