S
Sarwat Afridi
Researcher at Aix-Marseille University
Publications - 6
Citations - 79
Sarwat Afridi is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Malaria & Gene. The author has an hindex of 5, co-authored 6 publications receiving 66 citations. Previous affiliations of Sarwat Afridi include French Institute of Health and Medical Research & Balochistan University of Information Technology, Engineering and Management Sciences.
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Journal ArticleDOI
Malaria resistance genes are associated with the levels of IgG subclasses directed against Plasmodium falciparum blood-stage antigens in Burkina Faso
Sarwat Afridi,Sarwat Afridi,Alexandre Atkinson,Alexandre Atkinson,Séverine Garnier,Séverine Garnier,Francis Fumoux,Pascal Rihet,Pascal Rihet +8 more
TL;DR: The hypothesis that some polymorphisms affect malaria resistance through their effect on the acquired immune response is supported, and the results pave the way towards further comprehension of genetic control of an individual’s humoral response against malaria.
Journal ArticleDOI
Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso
Alexandre Atkinson,Alexandre Atkinson,Séverine Garnier,Séverine Garnier,Sarwat Afridi,Sarwat Afridi,Francis Fumoux,Pascal Rihet,Pascal Rihet +8 more
TL;DR: Genetic variants of HS3ST3A1 and HS3 ST3B1 are associated with P. falciparum parasitaemia, which suggests that those variants alter both the function of heparan sulphate proteoglycans and P. Falconerum parasitemia in humans.
Journal ArticleDOI
Evidence for epistasis between hemoglobin C and immune genes in human P. falciparum malaria: a family study in Burkina Faso
Alexandre Atkinson,Alexandre Atkinson,M Barbier,Sarwat Afridi,Sarwat Afridi,Francis Fumoux,Pascal Rihet,Pascal Rihet +7 more
TL;DR: The findings suggest an interaction between HbC and genes influencing the activation of effector cells for phenotypes related to mild malaria.
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Natural killer cells in acute myeloid leukemia patients: from phenotype to transcriptomic analysis.
Geoffroy Venton,Yasmine Labiad,J Colle,A. Fino,Sarwat Afridi,Magali Torres,S. Monteuil,Béatrice Loriod,Nicolas Fernandez-Nunez,Laure Farnault,Pierre Suchon,J. C. Mattei,Pascal Rihet,Aurélie Bergon,Cong Tu Nguyen,Céline Baier,Régis Costello +16 more
TL;DR: Results are encouraging regarding in vitro AML-NK cytotoxicity restoration and provide a new conceptual support for innovative cellular therapy based on in vitro NK cells expansion before their reinfusion in AML patients.
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Beyond genome-wide scan: Association of a cis-regulatory NCR3 variant with mild malaria in a population living in the Republic of Congo.
Sabrina Baaklini,Sabrina Baaklini,Sarwat Afridi,Sarwat Afridi,Thy Ngoc Nguyen,Thy Ngoc Nguyen,Felix Koukouikila-Koussounda,Mathieu Ndounga,Jean Imbert,Jean Imbert,Magali Torres,Magali Torres,Lydie Pradel,Lydie Pradel,Francine Ntoumi,Francine Ntoumi,Pascal Rihet,Pascal Rihet +17 more
TL;DR: The association of rs2736191 with mild malaria in a Congolese cohort and its potential cis-regulatory effect are confirmed and support the hypothesis that genetic variation within natural killer cell receptors alters malaria resistance in humans.