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Satoshi Ikemoto

Researcher at National Institute on Drug Abuse

Publications -  72
Citations -  8390

Satoshi Ikemoto is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Ventral tegmental area & Nucleus accumbens. The author has an hindex of 36, co-authored 65 publications receiving 7739 citations. Previous affiliations of Satoshi Ikemoto include United States Department of Health and Human Services & Bowling Green State University.

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Synergistic interaction between baclofen administration into the median raphe nucleus and inconsequential visual stimuli on investigatory behavior of rats.

TL;DR: Baclofen administration into the MR or DR increased investigatory behavior induced by visual stimuli, and Stimulation of GABAB receptors in the MR and DR appears to disinhibit the motivational process involving stimulus–approach responses.
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Seeking motivation and reward: Roles of dopamine, hippocampus, and supramammillo-septal pathway

TL;DR: In this article , the authors describe how novel stimuli and uncertainty trigger seeking motivation and how these neural substrates modulate information-seeking behavior and propose the concept of environment prediction error as a framework to understand informationseeking processes.
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Median Raphe Nonserotonergic Neurons Modulate Hippocampal Theta Oscillations

TL;DR: This study on male mice revealed a more complex framework indicating roles of nonserotonergic MnR outputs in regulating HTO, and found that nonselective optogenetic activation of MnR neurons at theta frequency increased HTO amplitude.
Posted ContentDOI

Medial Prefrontal Cortex Interacts with the Anteromedial Thalamus in Motivation and Dopaminergic Activity

TL;DR: The experiments characterize the circuits of the PFC regulating motivation, reinforcement and dopamine activity, revealing a novel cortico-thalamic loop that is found in human participants who watched reinforcing videos.
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Regulation of negative emotional behavior.

TL;DR: Examination of a neglected neuron type in the MRR shows that these MRR-vGLUT2 neurons have a vital role in the regulation of negative emotional states, which have considerable implications for understanding psychiatric illnesses, particularly anxiety and mood disorders.