S
Savita Khanna
Researcher at Indiana University
Publications - 165
Citations - 12807
Savita Khanna is an academic researcher from Indiana University. The author has contributed to research in topics: Wound healing & Vitamin E. The author has an hindex of 58, co-authored 154 publications receiving 11345 citations. Previous affiliations of Savita Khanna include University of California, Berkeley & Ohio State University.
Papers
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Journal ArticleDOI
MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue
Sashwati Roy,Savita Khanna,Syed-Rehan A. Hussain,Sabyasachi Biswas,Ali Azad,Cameron Rink,Surya Gnyawali,Shani Shilo,Gerard J. Nuovo,Chandan K. Sen +9 more
TL;DR: This work constitutes the first report describing changes in miR expression in response to IR in the mouse heart, showing that miR-21 regulates MMP-2 expression in CFs of the infarct zone via a PTEN pathway.
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Tocotrienols: Vitamin E Beyond Tocopherols
TL;DR: An expanding body of evidence support that members of the vitamin E family are functionally unique, and title claims in manuscripts should be limited to the specific form of vitamin E studied.
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Macrophage dysfunction impairs resolution of inflammation in the wounds of diabetic mice.
Savita Khanna,Sabyasachi Biswas,Yingli Shang,Eric Collard,Ali Azad,Courtney Y. Kauh,Vineet Bhasker,Gayle M. Gordillo,Chandan K. Sen,Sashwati Roy +9 more
TL;DR: First evidence is presented demonstrating that diabetic wounds suffer from dysfunctional macrophage efferocytosis resulting in increased apoptotic cell burden at the wound site, which prolongs the inflammatory phase and complicates wound healing.
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Dermal Wound Healing Is Subject to Redox Control
TL;DR: This work presents the first in vivo evidence indicating that strategies to influence the redox environment of the wound site may have a bearing on healing outcomes.
Journal ArticleDOI
Copper-induced vascular endothelial growth factor expression and wound healing.
Chandan K. Sen,Savita Khanna,Mika Venojärvi,Prashant Trikha,E. Christopher Ellison,Thomas K. Hunt,Sashwati Roy +6 more
TL;DR: First evidence showing that inducible VEGF expression is sensitive to copper is presented and that the angiogenic potential of copper may be harnessed to accelerate dermal wound contraction and closure is presented.