Scott Seki

TL;DR: This study demonstrates that longitudinal iPOP can be used to interpret healthy and diseased states by connecting genomic information with additional dynamic omics activity and reveals extensive heteroallelic changes during healthy and disease states and an unexpected RNA editing mechanism.

TL;DR: These phase 1 data demonstrate that rush OIT to multiple foods with 16 weeks of treatment with omalizumab could allow for a fast desensitization in subjects with multiple food allergies.

TL;DR: Preliminary data show oral immunotherapy using multiple food allergens simultaneously to be feasible and relatively safe when performed in a hospital setting with trained personnel.

TL;DR: Examination of in vivo immunological changes that occur during OV treatment of 14 children with PSC and IBD support immune-related pathophysiology of PSC with IBD, which is responsive to OV.

TL;DR: Signal transducer and activator of transcription (STAT) comprises a family of universal transcription factors that help cells sense and respond to environmental signals, and a novel, unique role for STAT5A is found in binding to genes involved in neural development and function, while STAT5B appears to play a distinct role in T cell development andfunction via DOCK8, SNX9, FOXP3 and IL2RA binding.