Lihua Jiang

TL;DR: This study demonstrates that longitudinal iPOP can be used to interpret healthy and diseased states by connecting genomic information with additional dynamic omics activity and reveals extensive heteroallelic changes during healthy and disease states and an unexpected RNA editing mechanism.

TL;DR: A mathematical expression is derived to compute PrediXcan results using summary data, and the effects of gene expression variation on human phenotypes in 44 GTEx tissues and >100 phenotypes are investigated.

TL;DR: The feasibility of high-throughput human proteome quantification is demonstrated that, when integrated with DNA variation and transcriptome information, adds a new dimension to the characterization of gene expression regulation.

TL;DR: The Human Tumor Atlas Network (HTAN), part of the NCI Cancer Moonshot Initiative, will establish a clinical, experimental, computational, and organizational framework to generate informative and accessible three-dimensional atlases of cancer transitions for a diverse set of tumor types.