S
Sean P. Gorman
Researcher at Queen's University Belfast
Publications - 201
Citations - 9323
Sean P. Gorman is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Biofilm & Biomaterial. The author has an hindex of 48, co-authored 201 publications receiving 8492 citations. Previous affiliations of Sean P. Gorman include Queen's University.
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The effects of three non-antibiotic, antimicrobial agents on the surface hydrophobicity of certain micro-organisms evaluated by different methods.
TL;DR: Comparison of the three recognized techniques for hydrophobicity measurements revealed a better correlation between the results obtained with the BATH test and HIC than the results obtaining withThe BATH and SAT or SAT and Hic, however, these differences may be due to the inaccuracy associated with the visual assessment of results employed by the SAT.
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Novel porphyrin-incorporated hydrogels for photoactive intraocular lens biomaterials.
TL;DR: The apparently promising TPPS/DEAEMA:HEMA system is a poor candidate for clinical application as a postoperative antibacterial treatment for intraocular lenses while the apparently equivalent cationic system TMPyP/MAA: HEMA displays all the required properties.
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Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro.
Maria Prencipe,Patricia Fitzpatrick,Sean P. Gorman,M Mosetto,Rut Klinger,Fiona Furlong,Michele Harrison,Darran P. O'Connor,I. B. Roninson,Jacintha O'Sullivan,Amanda McCann +10 more
TL;DR: It is shown that MAD2 down-regulation induces premature senescence in the MCF7 breast epithelial cancer cell line and compromised MAD2 levels induce a population of senescent cells resistant to paclitaxel.
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A comparative study of the microbial antiadherence capacities of three antimicrobial agents.
TL;DR: The antimicrobioal agents, taurolidine, chlorhexidine and povidone‐iodine exhibited significant anti‐adherence activity which was concentration dependent and consideration of the skewness coefficient and percentage clear epithelial cells indicated that the agents exhibited a broadly based anti-adherence capacity.
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Role of physiological conditions in the oropharynx on the adherence of respiratory bacterial isolates to endotracheal tube poly(vinyl chloride).
TL;DR: It is imperative that the physiological conditions predominating in the clinical area of biomaterial use be considered when investigating device biocompatibility and alternative biomaterials or surface modifications appear necessary for the desired improvements in ET tube effectiveness.