S
Seiki Takahashi
Publications - 7
Citations - 120
Seiki Takahashi is an academic researcher. The author has contributed to research in topics: Sharpless asymmetric dihydroxylation & Nicotinic acetylcholine receptor. The author has an hindex of 3, co-authored 7 publications receiving 119 citations.
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A new asymmetric entry to 2-substituted piperidines. A concise synthesis of (+)-coniine, (−)-pelletierine, (+)-δ-coniceine, and (+)-epidihydropinidine
TL;DR: In this article, a new asymmetric route to 2-substituted piperidines involving the Sharpless asymmetric dihydroxylation (AD) of 5-hexenylazide 1 and an intramolecular aminocyclization as crucial steps is presented.
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Symmetry-Assisted Synthesis of C2-Symmetric trans-α,α‘-Bis(hydroxymethyl)pyrrolidine and -piperidine Derivatives via Double Sharpless Asymmetric Dihydroxylation of α,ω-Terminal Dienes†
TL;DR: In this article, a new strategy was developed for the synthesis of C2-symmetric trans-α,α-α-bis(hydroxymethyl)pyrrolidine and piperidine derivatives 1−3 starting from symmetric α,ω-terminal dienes 4−6.
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Total synthesis of pyrrolizidines 223H', 239K', 265H', and 267H' found in Madagascan frogs (Mantella) and their affinities for nicotinic acetylcholine receptor.
TL;DR: The total synthesis of pyrrolizidines 223H', 239K', 265H', and 267H' has been achieved starting from 1,5-hexadiene via a common synthetic intermediate 5.
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Symmetry-Assisted Synthesis of C2-Symmetric trans-α,α′-Bis(hydroxymethyl)pyrrolidine and -piperidine Derivatives via Double Sharpless Asymmetric Dihydroxylation of α,ω-Terminal Dienes.
TL;DR: In this article, a new strategy was developed for the synthesis of C2-symmetric trans-α,α-α-bis(hydroxymethyl)pyrrolidine and piperidine derivatives 1−3 starting from symmetric α,ω-terminal dienes 4−6.
Journal ArticleDOI
Catalytic asymmetric synthesis of both enantiomers of pyrrolizidines 223H', 239K', 265H', and 267H' found in Madagascan frogs (Mantella) and their affinities for nicotinic acetylcholine receptor
TL;DR: The asymmetric synthesis of pyrrolizidines 223H', 239K', 265H', and 267H' has been achieved starting from 1,5-hexadiene via a common synthetic intermediate 5 and the affinity of both enanthiomers of 1-4 for nicotinic acetylcholine receptor was evaluated.