S
Sergey V. Razin
Researcher at Russian Academy of Sciences
Publications - 352
Citations - 7349
Sergey V. Razin is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Gene & Chromatin. The author has an hindex of 41, co-authored 333 publications receiving 6332 citations. Previous affiliations of Sergey V. Razin include International Centre for Genetic Engineering and Biotechnology & Russian Academy.
Papers
More filters
Journal ArticleDOI
Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
Ilya M. Flyamer,Johanna Gassler,Maxim Imakaev,Hugo B. Brandão,Sergey V. Ulianov,Nezar Abdennur,Sergey V. Razin,Sergey V. Razin,Leonid A. Mirny,Leonid A. Mirny,Kikuë Tachibana-Konwalski +10 more
TL;DR: In this paper, a single-nucleus Hi-C (high-resolution chromosome conformation capture) protocol was developed to study three-dimensional chromatin organization in rare cell types.
Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
Ilya M. Flyamer,Johanna Gassler,Maxim Imakaev,Hugo B. Brandão,Sergey V. Ulianov,Nezar Abdennur,Sergey V. Razin,Sergey V. Razin,Leonid A. Mirny,Leonid A. Mirny,Kikuë Tachibana-Konwalski +10 more
TL;DR: It is shown that chromatin architecture is uniquely reorganized during the oocyte-to-zygote transition in mice and is distinct in paternal and maternal nuclei within single-cell zygotes, demonstrating that the global chromatin organization of zygote nuclei is fundamentally different from that of other interphase cells.
Journal ArticleDOI
Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains
Sergey V. Ulianov,Ekaterina Khrameeva,Alexey A. Gavrilov,Ilya M. Flyamer,Pavel Kos,Elena A. Mikhaleva,Aleksey A. Penin,Maria D. Logacheva,Maria D. Logacheva,Maxim Imakaev,Alexander V. Chertovich,Mikhail S. Gelfand,Yuri Y. Shevelyov,Sergey V. Razin +13 more
TL;DR: The mechanism of TAD self-assembly is proposed based on the ability of nucleosomes from inactive chromatin to aggregate, and lack of this ability in acetylated nucleosomal arrays, and this hypothesis is tested by polymer simulations.
Journal ArticleDOI
Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila
Sergey V. Ulianov,Sergey V. Ulianov,Semen A. Doronin,Ekaterina Khrameeva,Ekaterina Khrameeva,Pavel Kos,Artem V. Luzhin,Sergei S. Starikov,Aleksandra A. Galitsyna,V V Nenasheva,Artem A. Ilyin,Ilya M. Flyamer,Elena A. Mikhaleva,Mariya D. Logacheva,Mariya D. Logacheva,Mariya D. Logacheva,Mikhail S. Gelfand,Mikhail S. Gelfand,Mikhail S. Gelfand,Alexander V. Chertovich,Alexey A. Gavrilov,Sergey V. Razin,Sergey V. Razin,Yuri Y. Shevelyov +23 more
TL;DR: Evidence is provided that disruption of the NL in Drosophila cells leads to overall chromatin compaction and repositioning from the nuclear envelope, whereas lamina-associated regions become less compacted and transcription within them is increased.
Journal ArticleDOI
Replication origins are attached to the nuclear skeleton
TL;DR: DNA fragments containing replication origins (oriDNA) were isolated from a chicken erythroblast cell line by a modified procedure of Zannis-Hadjopoulos et al. and found to coincide with the previously established positions of permanent sites of DNA attachment to the nuclear matrix.