S
Severin Pinilla
Researcher at University of Bern
Publications - 40
Citations - 1085
Severin Pinilla is an academic researcher from University of Bern. The author has contributed to research in topics: Medicine & Mesenchymal stem cell. The author has an hindex of 11, co-authored 30 publications receiving 929 citations. Previous affiliations of Severin Pinilla include Ludwig Maximilian University of Munich & University of Texas MD Anderson Cancer Center.
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Tissue-resident stem cells promote breast cancer growth and metastasis
Fabian Muehlberg,Yao-Hua Song,Alexander Krohn,Severin Pinilla,Lilly Droll,Xiaohong Leng,Max Seidensticker,Jens Ricke,Andrew M. Altman,Eswaran Devarajan,Weili Liu,Ralph B. Arlinghaus,Eckhard Alt +12 more
TL;DR: It is demonstrated that ASCs home to tumor site and promote tumor growth not only when co-injected locally but also when injected intravenously, indicating that the interaction of local tissue-resident stem cells with tumor stem cells plays an important role in tumor growth and metastasis.
Journal ArticleDOI
Adipose Tissue-Derived Stem Cells Differentiate into Carcinoma-Associated Fibroblast-Like Cells under the Influence of Tumor-Derived Factors
Constantin Jotzu,Eckhard Alt,Gabriel Welte,Jie Li,Bryan T. Hennessy,Eswaran Devarajan,Srinivasalu Krishnappa,Severin Pinilla,Lilly Droll,Yao-Hua Song +9 more
TL;DR: It is demonstrated that a significant percentage of hASCs differentiated into a CAF-like myofibroblastic phenotype and functional properties of CAFs, including the ability to promote tumor cell invasion in an in vitro invasion assay, as well as increased expression of stromal-cell-derived factor 1 and CCL5.
Journal ArticleDOI
Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion.
Severin Pinilla,Eckhard Alt,F.J. Abdul Khalek,Constantin Jotzu,Fabian Muehlberg,Christoph Beckmann,Yao-Hua Song +6 more
TL;DR: It is concluded that CCL5 plays a crucial role for tumor invasion in the interplay of tissue resident stem cells from the fat tissue and breast cancer cells.
The use of Facebook in medical education--a literature review.
TL;DR: There is no conclusive evidence as to whether medical students benefit from Facebook as a learning environment on higher competence levels, and it is suggested that digital professionalism be integrated in established and emerging competency-based catalogues.
The use of Facebook in medical education - A literature
TL;DR: In terms of learning and teaching environment, Facebook is well accepted by medical students as discussed by the authors and it is used to prepare for exams, share online material, discuss clinical cases, organize face-to-face sessions and exchange information on clerkships.