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Shabnam Tavassoli
Researcher at University of British Columbia
Publications - 5
Citations - 566
Shabnam Tavassoli is an academic researcher from University of British Columbia. The author has contributed to research in topics: Endoplasmic reticulum & Membrane protein. The author has an hindex of 4, co-authored 5 publications receiving 509 citations.
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Journal ArticleDOI
A conserved endoplasmic reticulum membrane protein complex (EMC) facilitates phospholipid transfer from the ER to mitochondria.
Sujoy Lahiri,Jesse T. Chao,Shabnam Tavassoli,Andrew K O Wong,Vineet Choudhary,Barry P. Young,Christopher J. R. Loewen,William A. Prinz +7 more
TL;DR: Tethering of the endoplasmic reticulum to mitochondria by a conserved endoplasmsic Reticulum complex is needed for the transfer of phospholipids between these organelles.
Journal ArticleDOI
Inheritance of cortical ER in yeast is required for normal septin organization.
TL;DR: It is found that cER inheritance is defective in cells lacking Scs2, a yeast homologue of the integral ER membrane protein VAP (vesicle-associated membrane protein–associated protein) conserved in all eukaryotes.
Journal ArticleDOI
Plasma membrane--endoplasmic reticulum contact sites regulate phosphatidylcholine synthesis.
Shabnam Tavassoli,Jesse T. Chao,Barry P. Young,Ruud C. Cox,William A. Prinz,Anton I.P.M. de Kroon,Christopher J. R. Loewen +6 more
TL;DR: It is shown that plasma membrane (PM)—ER contact sites in yeast are required for phosphatidylcholine synthesis and regulate the activity of theosphatidylethanolamine N‐methyltransferase enzyme, Opi3, which localizes to PM–ER contacts where it might facilitate in trans catalysis byOpi3.
Journal ArticleDOI
Polarization of the Endoplasmic Reticulum by ER-Septin Tethering
Jesse T. Chao,Andrew K O Wong,Shabnam Tavassoli,Barry P. Young,Adam T. Chruscicki,Nancy N. Fang,LeAnn J. Howe,Thibault Mayor,Leonard J. Foster,Christopher J. R. Loewen +9 more
TL;DR: It is shown that a direct interaction between the ER protein Scs2 and the septin Shs1 creates the ER diffusion barrier in yeast, which in neurons controls glutamate signaling in dendritic spines.
Journal ArticleDOI
A high-throughput method to globally study the organelle morphology in S. cerevisiae
TL;DR: This work crosses a GFP-tagged mitochondrial marker to a high-density array of 4,672 nonessential gene deletion mutants by robotic replica pinning and recovers both alleles, so that each haploid single mutant contains Apc1-GFP incorporated at its genomic locus.