S
Shamba Gupta
Researcher at Rutgers University
Publications - 10
Citations - 125
Shamba Gupta is an academic researcher from Rutgers University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 4, co-authored 6 publications receiving 75 citations. Previous affiliations of Shamba Gupta include Bose Institute.
Papers
More filters
Journal ArticleDOI
Essential protein SepF of mycobacteria interacts with FtsZ and MurG to regulate cell growth and division
Shamba Gupta,Srijon Kaushik Banerjee,Ayan Chatterjee,Arun Kumar Sharma,Manikuntala Kundu,Joyoti Basu +5 more
TL;DR: In vitro and in vivo assays showed that Rv2147c (or SepF) of Mycobacterium tuberculosis interacts with the principal driver of cytokinesis, FtsZ, and interacted with MurG, a peptidoglycan-synthesizing enzyme, both in vitro andIn vivo, suggesting that SepF could serve as a link between cell division and peptidglycan synthesis.
Journal ArticleDOI
MtrA, an essential response regulator of the MtrAB two-component system, regulates the transcription of resuscitation-promoting factor B of Mycobacterium tuberculosis.
Arun Kumar Sharma,Ayan Chatterjee,Shamba Gupta,Rajdeep Banerjee,Sukhendu Mandal,Jayanta Mukhopadhyay,Joyoti Basu,Manikuntala Kundu +7 more
TL;DR: It is demonstrated that rpfB transcription is regulated by MtrA - the response regulator of the essential two-component system MtrAB, and it is suggested that its transcription possibly occurs in a SigB-dependent manner.
Journal ArticleDOI
Mycobacterial extracellular vesicles and host pathogen interactions
TL;DR: This minireview will summarize the current understanding of mycobacterial EV biology and roles in pathogenesis and will discuss their potential therapeutic applications.
Journal ArticleDOI
Extracellular vesicles in the context of Mycobacterium tuberculosis infection.
TL;DR: The current evidence supporting an important role of mycobacterial EVs in modulating cellular immune response is discussed, the challenges and recent advances in understanding the mechanisms of vesicle biogenesis and the implications for development of new preventive and therapeutic tools against TB are discussed.
Journal ArticleDOI
Activation and Regulation of NLRP3 by Sterile and Infectious Insults
TL;DR: The existing knowledge about the mechanism of activation of NLRP3 and its regulation during activation by infectious and sterile triggers is summarized.