S
Sharad S. Pachore
Researcher at Dr. Reddy's Laboratories
Publications - 8
Citations - 42
Sharad S. Pachore is an academic researcher from Dr. Reddy's Laboratories. The author has contributed to research in topics: Indole test & Thionyl. The author has an hindex of 3, co-authored 8 publications receiving 32 citations. Previous affiliations of Sharad S. Pachore include Andhra University.
Papers
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Journal ArticleDOI
Synthesis and Optimization of Canagliflozin by Employing Quality by Design (QbD) Principles
Dattatray S. Metil,Dattatray S. Metil,Swapnil Panditrao Sonawane,Sharad S. Pachore,Aaseef Mohammad,Vilas Hareshwar Dahanukar,Peter Joseph Mccormack,Ch. Venkatramana Reddy,Rakeshwar Bandichhor +8 more
TL;DR: In this paper, a synthesis and process optimization of canagliflozin via purified open ring intermediate is described, and the process is optimized by employing quality by design (QbD) methodologies, and a telescopic strategy is executed for the first three and last two steps in a total six-step sequence.
Journal ArticleDOI
One pot oxidative dehydration - oxidation of polyhydroxyhexanal oxime to polyhydroxy oxohexanenitrile: A versatile methodology for the facile access of azasugar alkaloids.
Sandip R. Khobare,Sandip R. Khobare,Vikas Gajare,E. Vishnuvardhan Reddy,Rajender Datrika,Malavika Banda,Vidavalur Siddaiah,Sharad S. Pachore,Upadhya Timanna,Vilas Hareshwar Dahanukar,U. K. Syam Kumar +10 more
TL;DR: This oxidative dehydration-oxidation and reductive heteroannulation methodology is successfully utilized for the total synthesis of 1-deoxynojirimycin (1b), miglitol (2) and miglustat (3).
Patent
Process for the preparation of sglt2 inhibitors
Srinivas Oruganti,Bhaskar Kandagatla,Vilas Hareshwar Dahanukar,Praveen Cherukupally,Asif Mohammad,Venu Nalivela,Murali Konakalla,Debjit Basu,Venkata Annapurna Sasikala Cheemalapati,Rakeshwar Bandichhor,Murugan Andiappan,Archan Dey,Ramakrishna Reddy Kaipu,Jithin Jose,Srividya Ramakrishnan,Rajashekhar Totad,Sharad S. Pachore,Sateesh Madavaram,Sravan Kumar Bandaru,Dattatray S. Metil,Peter Joseph Mccormack,Vishnu Vardhana Vema Reddy Eda +21 more
TL;DR: In this paper, a process for the preparation of SGLT2 inhibitors is described, together with a procedure for the synthesis of amorphous form of Canagliflozin.
Journal ArticleDOI
Three-Component Coupling–Oxidative Amidation–Heterocycloannulation: Synthesis of the Indole Alkaloids Hamacanthin A and trans-2,5-Bis(3′-Indolyl)piperazine
TL;DR: In this article, the synthesis of antifungal marine bis(indole) alkaloids, hamacanthin A and trans-2,5-bis(3′-indolyl)piperazine is described.
Journal ArticleDOI
Successful utilization of $$\upbeta $$ β -ketonitrile in Biginelli reaction: synthesis of 5-cyanodihydropyrimidine
Sharad S. Pachore,Sharad S. Pachore,Narendra Bhalchandra Ambhaikar,Vidavalur Siddaiah,Sandip R. Khobare,Sarvesh Kumar,Vilas Hareshwar Dahanukar,U. K. Syam Kumar +7 more
TL;DR: In this article, a multicomponent Biginelli reaction employing $$\upbeta $$ -ketonitrile with aromatic or non-enolizable aliphatic aldehydes and urea in the presence of CuCl to cyano substituted dihydropyrimidones has been developed.