Organic Process Research & Development 

TL;DR: Methods for introducing fluorine into organic molecules are reviewed, with an emphasis on preparation of compounds designed for biomedicinal applications.

TL;DR: In this article, a range of salts should be prepared for each new substance and their properties compared during a suitable pre-formulation program, where possible, where the salt form selected will influence other properties such as melting point, hygroscopicity, chemical stability, dissolution rate, solution pH, crystal form, and mechanical properties.

TL;DR: In this article, it has been demonstrated that a safer manufacturing of organic intermediates and APIs could be obtained under continuous flow conditions, where some s... can also be easily combined to other enabling technologies, such as microwave irradiation, supported reagents or catalysts, photochemistry, inductive heating, electrochemistry, new solvent systems, 3D printing, or microreactor technology.

TL;DR: From the discovery of ritonavir until the new drug application (NDA) filing, only one crystalline form was known to exist, and this new crystal form was designated as Form II.

TL;DR: The American Chemical Society Green Chemistry Institute's Pharmaceutical Roundtable has chosen process mass intensity (PMI) as the key, high-level metric for evaluating and benchmarking progress towards more sustainable manufacturing as mentioned in this paper.