S
Sharon L. Platton
Publications - 2
Citations - 1263
Sharon L. Platton is an academic researcher. The author has contributed to research in topics: Curcumin & Tricin. The author has an hindex of 2, co-authored 2 publications receiving 1167 citations.
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Journal ArticleDOI
Phase I Clinical Trial of Oral Curcumin: Biomarkers of Systemic Activity and Compliance
Ricky A. Sharma,Stephanie A. Euden,Sharon L. Platton,Darren N. Cooke,Aisha Shafayat,Heather R. Hewitt,Timothy H. Marczylo,Bruno Morgan,David Hemingway,Simon M. Plummer,Munir Pirmohamed,Andreas J. Gescher,William P. Steward +12 more
TL;DR: A daily oral dose of 3.6 g of curcumin is advocated for Phase II evaluation in the prevention or treatment of cancers outside the gastrointestinal tract in patients with advanced colorectal cancer refractory to standard chemotherapies.
Journal ArticleDOI
The rice bran constituent tricin potently inhibits cyclooxygenase enzymes and interferes with intestinal carcinogenesis in ApcMin mice
Hong Cai,Mohammad Al-Fayez,Richard G. Tunstall,Sharon L. Platton,Peter Greaves,William P. Steward,Andreas J. Gescher +6 more
TL;DR: The results suggest that tricin should be further evaluated as a putative colorectal cancer chemopreventive agent.