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Sharon M. Brookes
Researcher at Animal and Plant Health Agency
Publications - 135
Citations - 5017
Sharon M. Brookes is an academic researcher from Animal and Plant Health Agency. The author has contributed to research in topics: Virus & Influenza A virus subtype H5N1. The author has an hindex of 38, co-authored 123 publications receiving 4443 citations. Previous affiliations of Sharon M. Brookes include World Organisation for Animal Health & World Health Organization.
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Journal ArticleDOI
Efficient infection of cells in culture by type O foot-and-mouth disease virus requires binding to cell surface heparan sulfate.
Terry Jackson,Fiona M. Ellard,Robin Abu Ghazaleh,Sharon M. Brookes,Wendy Blakemore,Amanda H. Corteyn,David I. Stuart,John Newman,Andandrew M. Q. King +8 more
TL;DR: The results show that entry of type O FMDV into cells is a complex process and suggest that the initial contact with the cell surface is made through heparan sulfate.
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Abundance of an endogenous retroviral envelope protein in placental trophoblasts suggests a biological function.
TL;DR: The evolutionary conservation and abundant expression of this endogenous retroviral protein in a specific cell type support the concept of a biological function and suggest that ERV-3 might form part of the placental immunosuppressive barrier between mother and foetus.
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Case report: isolation of a European bat lyssavirus type 2a from a fatal human case of rabies encephalitis.
Anthony R. Fooks,Lorraine M. McElhinney,Derrick J. Pounder,Christopher Finnegan,Karen L. Mansfield,Nicholas Johnson,Sharon M. Brookes,G. Parsons,Kathleen White,P. G. McIntyre,Dilip Nathwani +10 more
TL;DR: A 55‐year‐old bat conservationist was admitted to Ninewells Hospital, Dundee, Scotland, with an acute haematemesis and gave a 5‐day history of pain and paraesthesia in the left arm, followed by increasing weakness of his limbs with evidence of an evolving encephalitis with cerebellar involvement.
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Replication, pathogenesis and transmission of pandemic (H1N1) 2009 virus in non-immune pigs.
Sharon M. Brookes,Alejandro Núñez,Bhudipa Choudhury,Bhudipa Choudhury,Mikhail Matrosovich,Stephen Essen,Derek Clifford,Marek J. Slomka,Gaelle Kuntz-Simon,Fanny Garcon,Bethany J. Nash,Amanda Hanna,Peter M. H. Heegaard,Stéphane Quéguiner,Chiara Chiapponi,Michel Bublot,Jaime Maldonado Garcia,Rebecca A. Gardner,Emanuela Foni,Willie Loeffen,Lars Erik Larsen,Kristien Van Reeth,Jill Banks,Richard M. Irvine,Ian H. Brown +24 more
TL;DR: It is demonstrated that extant H1N1/09 is fully capable of becoming established in global pig populations and the roles of viral receptor specificity in both transmission and tissue tropism are shown.
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European bat lyssaviruses: an emerging zoonosis.
TL;DR: It is clear that EBLV in bats cannot be eliminated using conventional strategies similar to the control programmes based on vaccine baits used for fox rabies in Europe during the 1980s, and should be treated immediately with rabies post-exposure treatment and the bat, where possible, retained for laboratory analysis.