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Shawn Cunningham
Researcher at Johns Hopkins University
Publications - 5
Citations - 676
Shawn Cunningham is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Nevirapine & Genotype. The author has an hindex of 5, co-authored 5 publications receiving 670 citations.
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Journal ArticleDOI
Selection and fading of resistance mutations in women and infants receiving nevirapine to prevent HIV-1 vertical transmission (HIVNET 012).
Susan H. Eshleman,Martin Mracna,Laura Guay,Martina Deseyve,Shawn Cunningham,Mark Mirochnick,Philippa Musoke,Thomas Fleming,Mary Glenn Fowler,Lynne M. Mofenson,Francis Mmiro,J. Brooks Jackson +11 more
TL;DR: NVPR was detected more frequently in infants than women following NVP prophylaxis, and different patterns of NVPR mutations were detected in women versus infants, and NVP-resistant HIV-1 faded from detection in women and infants over time.
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Impact of Human Immunodeficiency Virus Type 1 (HIV-1) Subtype on Women Receiving Single-Dose Nevirapine Prophylaxis to Prevent HIV-1 Vertical Transmission (HIV Network for Prevention Trials 012 Study)
Susan H. Eshleman,Graziella Becker-Pergola,Martina Deseyve,Laura Guay,Martin Mracna,Thomas Fleming,Thomas Fleming,Shawn Cunningham,Philippa Musoke,Francis Mmiro,J. Brooks Jackson +10 more
TL;DR: Examination of the relationship between HIV-1 subtype, MTCT, and the development of Nvp resistance (Nvp(R) among women enrolled in HIVNET 012 finds no apparent difference in the rate of MTCT among women with subtype A versus D.
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Performance of the Applied Biosystems ViroSeq Human Immunodeficiency Virus Type 1 (HIV-1) Genotyping System for Sequence-Based Analysis of HIV-1 in Pediatric Plasma Samples
Shawn Cunningham,Bonnie J. Ank,Dan Lewis,Wei Lu,Michael Wantman,JoAnn Dileanis,J. Brooks Jackson,Paul Palumbo,Paul Krogstad,Susan H. Eshleman +9 more
TL;DR: This genotyping system performs well for analysis of HIV-1 in pediatric plasma samples, including those with low volume and low viral load, and should facilitate studies of HIV -1 drug resistance.
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Analysis of human immunodeficiency virus type 1 drug resistance in children receiving nucleoside analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir (Pediatric AIDS Clinical Trials Group 377).
Susan H. Eshleman,Paul Krogstad,J. Brooks Jackson,You-Gan Wang,Sophia Lee,Lee Jen Wei,Shawn Cunningham,Michael Wantman,Andrew Wiznia,George M. Johnson,Sharon A Nachman,Paul Palumbo +11 more
TL;DR: In Pediatric AIDS Clinical Trials Group 377, children were randomized to 4 treatment arms that included different combinations of stavudine, lamivudine (3TC), nevirapine (Nvp), nelfinavir (Nfv), and ritonavir (Rtv) as mentioned in this paper.
Journal ArticleDOI
Identification of Ugandan HIV Type 1 Variants with Unique Patterns of Recombination in pol Involving Subtypes A and D
Susan H. Eshleman,Matthew J. Gonzales,Graziella Becker-Pergola,Shawn Cunningham,Laura Guay,J. Brooks Jackson,Robert W. Shafer +6 more
TL;DR: The large number of different types of pol recombinants identified suggests that recombination occurs readily in the pol region, and demonstrates their evolutionary stability.