S
Sheldon R. Pinnell
Researcher at Duke University
Publications - 98
Citations - 6291
Sheldon R. Pinnell is an academic researcher from Duke University. The author has contributed to research in topics: Ascorbic acid & Lysyl hydroxylase. The author has an hindex of 40, co-authored 98 publications receiving 5921 citations. Previous affiliations of Sheldon R. Pinnell include L'Oréal & Durham University.
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Cutaneous photodamage, oxidative stress, and topical antioxidant protection
TL;DR: This scientific review summarizes what is known about how photodamage occurs; why sunscreens--the current gold standard of photoprotection--are inadequate; and how topical AOs help protect against skin cancer and photoaging changes.
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Topical vitamin C protects porcine skin from ultraviolet radiation‐induced damage
TL;DR: Evidence is provided that the vitamin C levels of the skin can be severely depleted after UV irradiation, which would lower this organ's innate protective mechanism as well as leaving it at risk of impaired healing after photoinduced damage.
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Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin
Fu Hsiung Lin,Jing Yi Lin,Ravindra D. Gupta,Joshua A. Tournas,James A. Burch,M. Angelica Selim,Nancy A. Monteiro-Riviere,James M. Grichnik,Jan Zielinski,Sheldon R. Pinnell +9 more
TL;DR: This combination of pure natural low molecular weight antioxidants provides meaningful synergistic protection against oxidative stress in skin and should be useful for protection against photoaging and skin cancer.
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UV photoprotection by combination topical antioxidants vitamin C and vitamin E
Jing Yi Lin,M. Angelica Selim,Christopher R. Shea,James M. Grichnik,Mostafa M. Omar,Nancy A. Monteiro-Riviere,Sheldon R. Pinnell +6 more
TL;DR: Appreciable photoprotection can be obtained from the combination of topical vitamins C and E and it is suggested that these natural products may protect against skin cancer and photoaging.
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Evidence supporting zinc as an important antioxidant for skin
TL;DR: The evidence supporting zinc's antioxidant role in protecting against free radical‐induced oxidative damage is reviewed, and zinc protects against UV radiation, enhances wound healing, contributes to immune and neuropsychiatric functions, and decreases the relative risk of cancer and cardiovascular disease.