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Sheng Huang

Researcher at Guangxi University

Publications -  20
Citations -  2646

Sheng Huang is an academic researcher from Guangxi University. The author has contributed to research in topics: TAL effector & Xanthomonas oryzae. The author has an hindex of 13, co-authored 20 publications receiving 2312 citations. Previous affiliations of Sheng Huang include Iowa State University & Nancy-Université.

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TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

TL;DR: The creation and initial characterization of a group of rare-cutting, site-specific DNA nucleases produced by fusion of the restriction enzyme FokI endonuclease domain (FN) with the high-specificity DNA-binding domains of AvrXa7 and PthXo1 are reported.
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Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes

TL;DR: These studies expand the realm of verified TALEN activity from cultured human cells to an intact eukaryotic organism and suggest that low-cost, highly dependable dTALENs can assume a significant role for gene modifications of value in human and animal health, agriculture and industry.
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Rice xa13 Recessive Resistance to Bacterial Blight Is Defeated by Induction of the Disease Susceptibility Gene Os-11N3

TL;DR: Variations in the TAL effector repetitive domains are driven by selection to overcome both dominant and recessive forms of resistance to bacterial blight in rice, indicating that N3 proteins have a specific function in facilitating bacterial blight disease.
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Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens

TL;DR: The Stambomycins A-D gene cluster as mentioned in this paper is one of the largest polyketide biosynthetic gene clusters described to date, which is composed of 25 genes (nine of which encode PKSs).