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Sheng-Long Ye

Researcher at Fudan University

Publications -  102
Citations -  4019

Sheng-Long Ye is an academic researcher from Fudan University. The author has contributed to research in topics: Metastasis & Hepatocellular carcinoma. The author has an hindex of 30, co-authored 102 publications receiving 3746 citations. Previous affiliations of Sheng-Long Ye include Fudan University Shanghai Medical College & Chinese Ministry of Education.

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A decade's studies on metastasis of hepatocellular carcinoma.

TL;DR: A molecular signature that can classify metastatic HCC patients is generated, osteopontin is identified as a lead gene in the signature, and it is found that genes favoring metastasis progression were initiated in the primary tumors.
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Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97

TL;DR: Two clones of the same genetic background but with different biological behaviors were established, which could be valuable models for investigation on HCC metastasis.
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Experience of 1000 patients who underwent hepatectomy for small hepatocellular carcinoma

TL;DR: The authors' experience in patients who underwent hepatectomy for small HCC and the factors that influence or improve long term survival are summarized.
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New human hepatocellular carcinoma (HCC) cell line with highly metastatic potential (MHCC97) and its expressions of the factors associated with metastasis

TL;DR: A new human hepatocellular carcinoma (HCC) cell line with a highly metastatic potential was established from subcutaneous xenograft of a metastatic model of human HCC in nude mice by means of alternating cell culture in vitro and growth in nude mouse.
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Stepwise metastatic human hepatocellular carcinoma cell model system with multiple metastatic potentials established through consecutive in vivo selection and studies on metastatic characteristics

TL;DR: The establishment of this new cell line has completed the stepwise metastatic HCC cell mode system, which was characterized by a similar genetic background but with significant differences in spontaneous metastasis behavior and supports the theory that cancer metastasis is a highly selective dynamic process.