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Yinkun Liu

Researcher at Fudan University

Publications -  234
Citations -  7610

Yinkun Liu is an academic researcher from Fudan University. The author has contributed to research in topics: Metastasis & Hepatocellular carcinoma. The author has an hindex of 44, co-authored 230 publications receiving 6867 citations. Previous affiliations of Yinkun Liu include Shanghai Jiao Tong University & Chinese Ministry of Education.

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Journal ArticleDOI

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

Hui Yang, +13 more
- 31 Jan 2013 - 
TL;DR: The levels of 5hmC are dramatically reduced in human breast, liver, lung, pancreatic and prostate cancers when compared with the matched surrounding normal tissues and the substantial reduction of the expression of all three TET genes is revealed, revealing a possible mechanism for the reduced5hmC in cancer cells.
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A decade's studies on metastasis of hepatocellular carcinoma.

Zhao-You Tang, +18 more
- 01 Apr 2004 - 
TL;DR: A molecular signature that can classify metastatic HCC patients is generated, osteopontin is identified as a lead gene in the signature, and it is found that genes favoring metastasis progression were initiated in the primary tumors.
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Establishment of cell clones with different metastatic potential from the metastatic hepatocellular carcinoma cell line MHCC97

Ying-Yi Li, +7 more
- 15 Oct 2001 - 
TL;DR: Two clones of the same genetic background but with different biological behaviors were established, which could be valuable models for investigation on HCC metastasis.
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microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity

Jin Zhang, +8 more
- 12 Oct 2010 - 
TL;DR: miR-22, downregulated in HCC, has an anti-proliferative effect on HCC cells both in vitro and in vivo, and may have considerable potential in identification of the prognosis and application of cancer therapy for HCC patients.
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New human hepatocellular carcinoma (HCC) cell line with highly metastatic potential (MHCC97) and its expressions of the factors associated with metastasis

J Tian, +6 more
- 01 Nov 1999 - 
TL;DR: A new human hepatocellular carcinoma (HCC) cell line with a highly metastatic potential was established from subcutaneous xenograft of a metastatic model of human HCC in nude mice by means of alternating cell culture in vitro and growth in nude mouse.