S
Sherry Metzker
Researcher at Baylor College of Medicine
Publications - 1
Citations - 57
Sherry Metzker is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Sanger sequencing. The author has an hindex of 1, co-authored 1 publications receiving 53 citations.
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Termination of DNA synthesis by N6-alkylated, not 3′-O-alkylated, photocleavable 2′-deoxyadenosine triphosphates
Weidong Wu,Brian P. Stupi,Vladislav A. Litosh,Dena L. Mansouri,Demetra Farley,Sidney E. Morris,Sherry Metzker,Michael L. Metzker +7 more
TL;DR: A novel paradigm in RT chemistry is discovered, the attachment of a photocleavable, 2-nitrobenzyl group to the N6-position of 2′-deoxyadenosine triphosphate (dATP), which, upon incorporation, terminates DNA synthesis.