Shigeji Sato

TL;DR: In this paper, the authors proposed a sustained pulse-wise release pharmaceutical preparation, which comprises drug-containing polymeric material layers (layers A) and polymica material layers containing the drug in question only in a small amount or free of the drug (layer B) disposed alternatingly, with the whole surface extending in the direction perpendicular to the layer plane being coated with polymeric materials which is insoluble in water or scarcely soluble in water.

TL;DR: An equipment for administering solid or semisolid preparations under the skin, which comprises a solid needle (1) member with an acute tip end (1a), and a cylindrical member (3) slidably mounted on the needle member, is described in this paper.

TL;DR: In this article, a sustained-release preparation in the form of a needle-like or bar-like shape, which comprises an active ingredient and a pharmaceutically acceptable biodegradable carrier (e.g., proteins, polysaccharides and synthetic high molecular compounds, preferably collagen, atelocollagen, gelatin, and a mixture thereof) is presented.

TL;DR: The minipellet is applicable to various kinds of biologically active peptides and proteins and expected to facilitate their potential therapeutic use and is easily administered in the same way as conventional injections.

TL;DR: In this article, a sustained-release injection is proposed, which comprises a suspension of a powder comprising an active ingredient and a pharmaceutically acceptable biodegradable carrier (e.g. proteins, polysaccharides and synthetic high molecular compounds) in a viscous solvent for injection.