Yoshihiro Takada

TL;DR: In this article, the authors describe a device for administering solid or semisolid preparations in an organism subcutaneously, using a guide member adapted to be snugly accommodated within the lumen of a barrel.

TL;DR: In this paper, the authors proposed a sustained pulse-wise release pharmaceutical preparation, which comprises drug-containing polymeric material layers (layers A) and polymica material layers containing the drug in question only in a small amount or free of the drug (layer B) disposed alternatingly, with the whole surface extending in the direction perpendicular to the layer plane being coated with polymeric materials which is insoluble in water or scarcely soluble in water.

TL;DR: A solid sustained-release preparation in the form of a needle-like or bar-like shape, which consists essentially of an active ingredient and a pharmaceutically acceptable biodegradable carrier (e.g. proteins, preferably collagen, gelatin, and a mixture thereof) can be administered to the body or implanted into the body by injection or an injection-like method as mentioned in this paper.

TL;DR: An equipment for administering solid or semisolid preparations under the skin, which comprises a solid needle (1) member with an acute tip end (1a), and a cylindrical member (3) slidably mounted on the needle member, is described in this paper.

TL;DR: The minipellet is applicable to various kinds of biologically active peptides and proteins and expected to facilitate their potential therapeutic use and is easily administered in the same way as conventional injections.