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Shiu Feng Huang
Researcher at National Health Research Institutes
Publications - 9
Citations - 1607
Shiu Feng Huang is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 2, co-authored 2 publications receiving 1500 citations. Previous affiliations of Shiu Feng Huang include University of Texas Southwestern Medical Center.
Papers
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Journal ArticleDOI
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
Jonathan F. Bean,Cameron Brennan,Jin-Yuan Shih,Gregory J. Riely,Gregory J. Riely,Agnes Viale,Lu Wang,Dhananjay Chitale,Noriko Motoi,Noriko Motoi,Janos Szoke,Stephen Broderick,Marissa Balak,Wen Cheng Chang,Chong-Jen Yu,Adi F. Gazdar,Harvey I. Pass,Valerie W. Rusch,William L. Gerald,Shiu Feng Huang,Pan-Chyr Yang,Vincent Miller,Vincent Miller,Marc Ladanyi,Chih-Hsin Yang,William Pao,William Pao +26 more
TL;DR: Analysis of tumor samples from multiple independent patient cohorts and array-based comparative genomic hybridization suggest that MET amplification occurs independently of EGFRT790M mutations and that MET may be a clinically relevant therapeutic target for some patients with acquired resistance to gefitinib or erlotinib.
Journal Article
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
Jonathan F. Bean,Cameron Brennan,Jin-Yuan Shih,Gregory J. Riely,Agnes Viale,Lu Wang,Dhananjay Chitale,Noriko Motoi,Janos Szoke,Stephen Broderick,Marissa Balak,Wen Cheng Chang,Chong-Jen Yu,Adi F. Gazdar,Harvey I. Pass,Valerie W. Rusch,William L. Gerald,Shiu Feng Huang,Pan-Chyr Yang,Vincent Miller,Marc Ladanyi,Chih-Hsin Yang,William Pao +22 more
TL;DR: In this paper, the authors performed high-resolution genomic analysis (array-based comparative genomic hybridization; aCGH) of tissue samples from 12 patients who initially responded to gefitinib or erlotinib eventually developed acquired resistance.
Journal ArticleDOI
EGFR Mutation-Harboring Lung Cancer Cells Produce CLEC11A with Endothelial Trophic and Tumor-Promoting Activities
Tzu-yin Lin,Chi-Hwa Yang,Hsiao Chin Chou,Chun-Mei Cheng,Ya-Wen Liu,Jiz-Yuh Wang,Li–Rung Huang,Shih-Feng Tsai,Shiu Feng Huang,Yi-Rong Chen +9 more
TL;DR: It is reported that EGFR mutation-containing lung cancer cells produced CLEC11A with endothelial trophic and tumor-promoting activities, and results indicated that CLEC 11A was a factor of angiogenic potential and was involved in lung cancer tumorigenesis.
Journal ArticleDOI
Novel Paired Cell Lines for the Study of Lipid Metabolism and Cancer Stemness of Hepatocellular Carcinoma
Yun-Hsin Cheng,Ying-Chieh Ko,Hsiang-Ju Ku,Ching-Chun Huang,Yunqi Yao,Yijiao Liao,Ying-Tsong Chen,Shiu Feng Huang,Li–Rung Huang +8 more
TL;DR: Two novel HCC cell lines are described with distinct features of lipid metabolism related to cancer stemness and differential interplay with the immune system, and this syngeneic HCC mouse model is presented as a practical tool for the study of cancerstemness and discovery of new therapies targeting liver cancers.
Journal ArticleDOI
Reciprocal regulation of Daxx and PIK3CA promotes colorectal cancer cell growth
TL;DR: A mechanistic pathway of Daxx overexpression in CRC is identified and a reciprocal regulation between DaxX and PIK3CA for CRC cell growth is suggested.