Shixin Jiang

TL;DR: This is the first study that achieved such accurate BLT morphological reconstruction of orthotopic glioma without using any segmented tumor structure from any other structural imaging modalities as the prior for reconstruction guidance.

TL;DR: A l 2,1-norm optimization method using a priori information, mainly the structured sparsity of the fluorescent regions for FMT reconstruction, achieves accurate and desirable fluorescent source reconstruction, but also demonstrates enhanced robustness to noise.

TL;DR: The fused LASSO method (FLM) based on group sparsity prior not only takes advantage of the sparsity of the fluorescent sources, but also utilizes the structure of the sources, thus making the reconstruction results more accuracy and morphologically similar to the sources.

TL;DR: A novel compactly supported radial basis functions-based meshless method (MM) is proposed to implement the photon propagation model (PPM) of FMT and could obtain more similar surface fluorescence measurement with the golden standard (Monte-Carlo method).

TL;DR: An efficient method using variable splitting strategy as well as alternating direction strategy (VSAD) was proposed for FMT reconstruction and indicated that the reconstruction accuracy, the reconstruction robustness, and the reconstruction speed of FMT were satisfactory by using the proposed VSAD method.