S
Shoji Kagami
Researcher at University of Tokushima
Publications - 233
Citations - 5880
Shoji Kagami is an academic researcher from University of Tokushima. The author has contributed to research in topics: Glomerulonephritis & Integrin. The author has an hindex of 38, co-authored 226 publications receiving 5316 citations. Previous affiliations of Shoji Kagami include Kagawa University & Niigata University.
Papers
More filters
Journal ArticleDOI
Mutation of DNASE1 in people with systemic lupus erythematosus.
Koji Yasutomo,Takahiko Horiuchi,Shoji Kagami,Hiroshi Tsukamoto,Chinami Hashimura,Maki Urushihara,Yasuhiro Kuroda +6 more
TL;DR: Two patients with a heterozygous nonsense mutation in exon 2 ofDNASE1, decreased DNASE1 activity and an extremely high immunoglobulin G titer against nucleosomal antigens are described, consistent with the hypothesis that a direct connection exists between low activity of DNase1 and progression of human SLE.
Journal ArticleDOI
Possible Contributions of Reactive Oxygen Species and Mitogen-Activated Protein Kinase to Renal Injury in Aldosterone/Salt-Induced Hypertensive Rats
Akira Nishiyama,Li Yao,Yukiko Nagai,Kayoko Miyata,Masanori Yoshizumi,Shoji Kagami,Shoji Kagami,Shuji Kondo,Hideyasu Kiyomoto,Takatomi Shokoji,Shoji Kimura,Shoji Kimura,Masakazu Kohno,Youichi Abe +13 more
TL;DR: It is suggested that ROS and MAPK play a role in the progression of renal injury induced by chronic elevations in aldosterone, and eplerenone and tempol treatments normalized the activities of ERK1/2, JNK, and BMK1.
Journal ArticleDOI
Hydrogen Peroxide Stimulates c-Src-mediated Big Mitogen-activated Protein Kinase 1 (BMK1) and the MEF2C Signaling Pathway in PC12 Cells POTENTIAL ROLE IN CELL SURVIVAL FOLLOWING OXIDATIVE INSULTS
Yuki Suzaki,Masanori Yoshizumi,Shoji Kagami,A. Hajime Koyama,Yutaka Taketani,Hitoshi Houchi,Koichiro Tsuchiya,Eiji Takeda,Toshiaki Tamaki +8 more
TL;DR: Findings suggest that c-Src mediated BMK1 activation by H2O2 may counteract ischemic cellular damage probably through the activation of MEF2C transcription factor.
Journal ArticleDOI
Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population
Kayoko Tao,Mutsuko Fujii,Shin Ichi Tsukumo,Yoichi Maekawa,Kenji Kishihara,Yasutaka Kimoto,Takahiko Horiuchi,Hajime Hisaeda,Shizuo Akira,Shoji Kagami,Koji Yasutomo +10 more
TL;DR: The results indicate that the presence of the G allele at position +1174 of TLR9 predisposes humans to an increased risk of SLE, and it is speculated thatTLR9 normally prevents the development of human SLE.
Journal ArticleDOI
Nitrite is an alternative source of NO in vivo.
Koichiro Tsuchiya,Yasuhisa Kanematsu,Masanori Yoshizumi,Hideki Ohnishi,Kazuyoshi Kirima,Yuki Izawa,Michiyo Shikishima,Tatsuhiro Ishida,Shuji Kondo,Shoji Kagami,Yoshiharu Takiguchi,Toshiaki Tamaki +11 more
TL;DR: Results indicate that orally ingested nitrite can be an alternative to L-arginine as a source of NO in vivo and may explain, at least in part, the mechanism of the nitrite/nitrate-rich Dietary Approaches to Stop Hypertension diet-induced hypotensive effects.