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Showing papers by "Shosuke Suzuki published in 2020"


Journal ArticleDOI
06 Feb 2020-BMJ Open
TL;DR: The lost weight group had a lower risk than the remained overweight group and the gained weight group and did not carry statistically significant risks for knee pain, suggesting weight reduction and maintaining a normal BMI in middle age was important for preventing knee pain in women.
Abstract: Objectives To investigate whether body mass index (BMI) trajectory, lifestyle and reproductive factors are associated with knee pain risk among middle-aged women. Design Prospective study of the Japan Nurses’ Health Study (JNHS). Setting The JNHS investigates the health of female nurses in Japan. Biennial follow-up questionnaires are mailed to the participants. Participants The 7434 women aged over 40 years who responded to the 10-year self-administered follow-up questionnaire. Primary outcome measure Self-reported knee pain at the 10-year follow-up was the primary outcome. We analysed BMI (normal or overweight) trajectory data from a baseline survey to the 10-year follow-up survey using group-based trajectory modelling. Exposure measurements were BMI trajectory, BMI at age 18 years, lifestyle variables and reproductive history. Results BMI trajectories from baseline to the 10-year follow-up were divided into four groups: remained normal, remained overweight, gained weight or lost weight. At the 10-year follow-up, 1281 women (17.2%) reported knee pain. Multivariable logistic regression analysis revealed that compared with the remained normal group, multivariable-adjusted ORs (95% CI) of knee pain were 1.93 (1.60 to 2.33) for the remained overweight group, 1.60 (1.23 to 2.08) for the gained weight group and 1.40 (0.88 to 2.21) for the lost weight group. The attributable risk percent (95% CI) of the remained overweight group was 48.1% (37.3% to 57.0%) compared with the reference group of remained normal. Alcohol intake at baseline was significantly associated with knee pain. Conclusions The lost weight group had a lower risk than the remained overweight group and the gained weight group and did not carry statistically significant risks for knee pain. Weight reduction and maintaining a normal BMI in middle age was important for preventing knee pain in women.

5 citations


Journal ArticleDOI
TL;DR: Only the heaviest class, smoke ≥30 cigs or more a day, had significantly higher mean scores for vague complaints, short temper, anxiety, depression, mouth, eye, and neurotics, and Mortality risk of lung cancer was high in heavy smokers.
Abstract: The effects of smoking on physical and mental health were assessed in a cohort of 3,376 middle-aged men by a health questionnaire, the Total Health Index, and by mortality risk ratio. Participants were grouped into the four following smoking classes: never smoked, smoke 1–19, 20–29, and ≥30 cigarettes a day. The Index has 15 physical and mental symptom scales that assess his perceived health of respiratory organs, digestive organs, short temper, depression, aggressiveness, et al. Each scale score was calculated as the sum of the positive number of symptoms, and a higher score indicates more symptoms. Starting from never smoked class, mean respiratory organ scale score increase linearly depending on the heavier smoking classes. Mean digestive organ scale score and the other three scale scores also showed linear dose-response relationship with the three classes of increasing number of cigarettes smoked a day. The other seven scale scores showed not a linear but J-shaped dose-response relationship. The never-smoked, smoke 1–19, and 20–29 cigarettes per day classes showed no increased response; only the heaviest class, smoke ≥30 cigs or more a day, had significantly higher mean scores for vague complaints, short temper, anxiety, depression, mouth, eye, and neurotics. Mortality risk of lung cancer was also high in heavy smokers (RR=3.71). Men of depression included more heavy smokers than the other non-depression men (P=0.0014).

1 citations