S
Shu-Yang Wang
Researcher at Southern Medical University
Publications - 25
Citations - 930
Shu-Yang Wang is an academic researcher from Southern Medical University. The author has contributed to research in topics: Metastasis & Colorectal cancer. The author has an hindex of 14, co-authored 21 publications receiving 668 citations.
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Journal ArticleDOI
MicroRNA‐30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2
Wenting Liao,Ya-Ping Ye,Nian-Jie Zhang,Tingting Li,Shu-Yang Wang,Yan-Mei Cui,Lu Qi,Ping Wu,Hong-Li Jiao,Yi-Jun Xie,Chi Zhang,Jun-Xian Wang,Yanqing Ding +12 more
TL;DR: Functional and mechanistic links between miRNA‐30b and oncogene KRAS, PIK3CD and BCL2 in the pathogenesis of CRC were revealed and Restoration of miR‐30B expression may represent a promising therapeutic approach for targeting malignant CRC.
Journal ArticleDOI
Hsa_circ_001680 affects the proliferation and migration of CRC and mediates its chemoresistance by regulating BMI1 through miR-340
Xiangyu Jian,Han He,Jiehong Zhu,Qi Zhang,Zhongxin Zheng,Xiang-Jing Liang,Liuyan Chen,Meiling Yang,Kaiyue Peng,Zhaowen Zhang,Tengfei Liu,Ya-Ping Ye,Hong-Li Jiao,Shu-Yang Wang,Weijie Zhou,Yanqing Ding,Tingting Li +16 more
TL;DR: circ_001680 may be a promising diagnostic and prognostic marker to determine the success of irinotecan-based chemotherapy in colorectal carcinoma through BMI1 upregulation.
Journal ArticleDOI
microRNA-224 Promotes Cell Proliferation and Tumor Growth in Human Colorectal Cancer by Repressing PHLPP1 and PHLPP2
Wenting Liao,Tingting Li,Zheng-Gen Wang,Shu-Yang Wang,Mei-Rong He,Ya-Ping Ye,Lu Qi,Yan-Mei Cui,Ping Wu,Hong-Li Jiao,Chi Zhang,Yi-Jun Xie,Jun-Xian Wang,Yanqing Ding +13 more
TL;DR: Functional and mechanistic links between miRNA-224 and the tumor suppressors PHLPP1 and PHL PP2 in the pathogenesis of colorectal cancer are revealed.
Journal ArticleDOI
MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer
Tingting Li,Qiuhua Lai,Shu-Yang Wang,Juanjuan Cai,Zhi-Yuan Xiao,Danling Deng,Liuqing He,Hong-Li Jiao,Ya-Ping Ye,Li Liang,Yanqing Ding,Wenting Liao +11 more
TL;DR: Mechanistic links between miR-224 and Wnt/β-catenin in the pathogenesis of CRC through modulation of GSK3β and SFRP2 are showed.
Journal ArticleDOI
FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways
Yan-Mei Cui,Dan Jiang,Shi-Hong Zhang,Ping Wu,Ya-Ping Ye,Cui-Min Chen,Na Tang,Li Liang,Tingting Li,Lu Qi,Shu-Yang Wang,Hong-Li Jiao,Jie Lin,Yanqing Ding,Wenting Liao +14 more
TL;DR: It is revealed that both high expression and nuclear localization of FOXC2 were correlated to aggressive characteristics and poor survival of patients with CRC, suggesting that FoxC2 plays an essential role in CRC progression and may serve as a valuable clinical prognostic marker of this disease.