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Shuai Jiang
Researcher at Fourth Military Medical University
Publications - 82
Citations - 3966
Shuai Jiang is an academic researcher from Fourth Military Medical University. The author has contributed to research in topics: Melatonin & Cancer. The author has an hindex of 36, co-authored 79 publications receiving 2956 citations. Previous affiliations of Shuai Jiang include Northwest University (China) & Zhengzhou University.
Papers
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Journal ArticleDOI
The emerging role of Toll-like receptor 4 in myocardial inflammation
Yuefan Yang,J Lv,Shuai Jiang,Zhiqiang Ma,Dongjin Wang,Wei Hu,Chao Deng,Chongxi Fan,Shouyin Di,Yuanjie Sun,Wei Yi +10 more
TL;DR: The basic knowledge of the TLR4 gene is introduced and the activation and signaling pathways ofTLR4 in myocardial inflammation are described, which may be useful to further experimental research and to increase the potential of TLR 4 as a therapeutic target.
Journal ArticleDOI
Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice
Yang Yang,Shuai Jiang,Yushu Dong,Chongxi Fan,Lei Zhao,Xiangmin Yang,Juan Li,Shouyin Di,Liang Yue,Guobiao Liang,Russel J. Reiter,Yan Qu +11 more
TL;DR: Melatonin treatment attenuates cerebral IRI by reducing IR‐induced mitochondrial dysfunction through the activation of SIRT1 signaling, and is demonstrated to result in a well‐preserved mitochondrial membrane potential, mitochondrial Complex I activity, and mitochondrial cytochrome c level.
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A review of melatonin as a suitable antioxidant against myocardial ischemia–reperfusion injury and clinical heart diseases
Yang Yang,Yang Sun,Wei Yi,Yue Li,Chongxi Fan,Zhenlong Xin,Shuai Jiang,Shouyin Di,Yan Qu,Russel J. Reiter,Dinghua Yi +10 more
TL;DR: The information summarized in this review should serve as a comprehensive reference for the action of melatonin in cardioprotection and hopefully will contribute to the design of future experimental research.
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AMPK: Potential Therapeutic Target for Ischemic Stroke.
TL;DR: The basic structure, upstream regulators, and biological roles of AMPK are introduced and the relationship between AMPK and the neurovascular unit (NVU) is analyzed, followed by ethical issues, potential directions, and further prospects of AM PK.
Journal ArticleDOI
Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling.
Yushu Dong,Chongxi Fan,Wei Hu,Shuai Jiang,Zhiqiang Ma,Xiaolong Yan,Chao Deng,Shouyin Di,Zhenlong Xin,Guiling Wu,Yang Yang,Russel J. Reiter,Guobiao Liang +12 more
TL;DR: Melatonin treatment attenuates the EBI following SAH by inhibiting NLRP3 inflammasome‐associated apoptosis, which is reported to possess substantial anti‐inflammatory properties.