S
Shuran Zhang
Researcher at Johns Hopkins University School of Medicine
Publications - 3
Citations - 88
Shuran Zhang is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Chemistry & Dopaminergic. The author has an hindex of 1, co-authored 1 publications receiving 61 citations.
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Journal ArticleDOI
Adult Conditional Knockout of PGC-1α Leads to Loss of Dopamine Neurons
Haisong Jiang,Sung Ung Kang,Shuran Zhang,Senthilkumar S. Karuppagounder,Jinchong Xu,Yong Kyu Lee,Bong Gu Kang,Yunjong Lee,Jianmin Zhang,Olga Pletnikova,Juan C. Troncoso,Shelia Pirooznia,Shaida A. Andrabi,Valina L. Dawson,Ted M. Dawson +14 more
TL;DR: It is found that there are four different PGC-1α isoforms expressed in SH-SY5Y cells, and these four isoforms are expressed across subregions of mouse brain, and that P GC-1 α is essential for SNpc DA neuronal survival, possibly through the maintenance of mitochondrial function.
Journal ArticleDOI
Purine alkaloids in tea plants: component, biosynthetic mechanism and genetic variation
TL;DR: In this article , a review of the component, biosynthetic mechanism and genetic variation of purine alkaloids in tea plants is presented. But the potential application of genetic engineering and DNA markers developed based on the low caffeine TCS1 (tea caffeine synthesis gene) alleles for marker assisted selection (MAS), and cocoa tea and kucha in low caffeine/high theacrine tea cultivar breeding programs were also reviewed.
Journal ArticleDOI
Caffeic acid regulated respiration, ethylene and reactive oxygen species metabolism to suppress senescence of Malus domestica
TL;DR: In this paper , the variations of reactive oxygen species (ROS), respiration and ethylene metabolism in "Qiujin" apples after caffeic acid dipping were assessed, and it was shown that caffeic acids remarkably inhibited respiratory rate, ethylene release rate and hydrogen peroxide accumulation, but increased reduced glutathione and ascorbic acid contents in apples.