S
Shuzo Matsumoto
Researcher at Hokkaido University
Publications - 104
Citations - 2429
Shuzo Matsumoto is an academic researcher from Hokkaido University. The author has contributed to research in topics: Virus & Antibody. The author has an hindex of 24, co-authored 104 publications receiving 2368 citations. Previous affiliations of Shuzo Matsumoto include Nagoya City University & University of Nebraska Medical Center.
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Journal ArticleDOI
Epstein-Barr virus genome-positive T lymphocytes in a boy with chronic active EBV infection associated with Kawasaki-like disease
Hideaki Kikuta,Yuichi Taguchi,K. Tomizawa,K. Kojima,Nobuaki Kawamura,Akihito Ishizaka,Yukio Sakiyama,Shuzo Matsumoto,Shosuke Imai,Toshifumi Kinoshita,Shigeki Koizumi,Toyoro Osato,Ichiro Kobayashi,Isamu Hamada,Kanji Hirai +14 more
TL;DR: All the EBV-determined nuclear antigen (EBNA)-positive lymphocytes had exclusively CD4 antigen, as revealed by dual staining immunofluorescence analysis and Southern blot hybridization showed that the purified CD4+ cells harboured EBV genome.
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Successful Peripheral T-Lymphocyte–Directed Gene Transfer for a Patient With Severe Combined Immune Deficiency Caused by Adenosine Deaminase Deficiency
M. Onodera,Tadashi Ariga,Nobuaki Kawamura,Ichiro Kobayashi,Makoto Ohtsu,Masafumi Yamada,Atsushi Tame,Hirofumi Furuta,Motohiko Okano,Shuzo Matsumoto,Kotani H,McGarrity Gj,Blaese Rm,Yukio Sakiyama +13 more
TL;DR: The results obtained in this trial are in agreement with previously published observations and support the usefulness of T lymphocyte-directed gene transfer in the treatment of ADA-SCID.
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Severe chronic active Epstein-Barr virus infection syndrome.
Motohiko Okano,Shuzo Matsumoto,Toyoro Osato,Yukio Sakiyama,Geoffrey M. Thiele,David T. Purtilo +5 more
TL;DR: This enigmatic syndrome is characterized by persistent or intermittent fever, lymphadenopathy, and hepatosplenomegaly and primarily affects children and young adults and some patients develop B-cell or T-cell lymphoproliferation or lymphoma.
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Fatal Epstein-Barr Virus-Associated Hemophagocytic Syndrome
Hideaki Kikuta,Yukio Sakiyama,Shuzo Matsumoto,Tsutomu Oh-ishi,Takashi Nakano,Tetsurou Nagashima,Toshiaki Oka,Takashi Hironaka,Kanji Hirai +8 more
TL;DR: Six Japanese children with fatal Epstein-Barr virus (EBV)-associated hemophagocytic syndrome are described and clonality analysis of the EBV genome showed that EBV-infected cells proliferated monoclonally or biclonally in three examined patients.
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The inductive effect of interleukin-4 on IgG4 and IgE synthesis in human peripheral blood lymphocytes.
Akihito Ishizaka,Yukio Sakiyama,Masanori Nakanishi,K. Tomizawa,E Oshika,K. Kojima,Y Taguchi,Eman Kandil,Shuzo Matsumoto +8 more
TL;DR: Data indicates that IL‐4 plays an important regulatory role in both IgG subclass and IgE synthesis, and that recombinant interleukin‐4 enhances the enhancement of lgE synthesis.