S
Sijian Wang
Researcher at University of Texas Southwestern Medical Center
Publications - 4
Citations - 474
Sijian Wang is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Breast cancer & Immunohistochemistry. The author has an hindex of 3, co-authored 4 publications receiving 469 citations.
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Journal ArticleDOI
Laboratory assessment of the status of Her-2/neu protein and oncogene in breast cancer specimens: comparison of immunohistochemistry assay with fluorescence in situ hybridisation assays
Sijian Wang,M. H. Saboorian,Eugene P. Frenkel,Linda S. Hynan,Sefik T. Gokaslan,Raheela Ashfaq +5 more
TL;DR: This study suggests that the best approach is to combine both IHC and FISH assays; that is, to use the I HC assay as a triage step, followed by the PathVysion FISH assay to analyse the IHC medium and high positive cases.
Journal ArticleDOI
Assessment of HER-2/neu status in breast cancer. Automated Cellular Imaging System (ACIS)-assisted quantitation of immunohistochemical assay achieves high accuracy in comparison with fluorescence in situ hybridization assay as the standard.
Sijian Wang,M. Hossein Saboorian,Eugene P. Frenkel,Barbara Haley,Momin T. Siddiqui,Sefik T. Gokaslan,Frank H. Wians,Linda S. Hynan,Raheela Ashfaq,Raheela Ashfaq +9 more
TL;DR: A new image analyzer-assisted immunohistochemical quantitation method, using fluorescence in situ hybridization assay (FISH) as the standard, which represents a substantial improvement over the manual method for objective evaluation of the HER-2/neu status.
Journal ArticleDOI
Aneusomy 17 in Breast Cancer: Its Role in HER-2/neu Protein Expression and Implication for Clinical Assessment of HER-2/neu Status
Sijian Wang,M. Hossein Saboorian,Eugene P. Frenkel,Barbara Haley,Momin T. Siddiqui,Sefik T. Gokaslan,Linda S. Hynan,Raheela Ashfaq +7 more
TL;DR: Except in a certain subset of cases, aneusomy 17 probably is not a significant factor for HER-2/neu protein expression or for clinical assessment of HER- 2/neU status.