S
Silvia Lopes de Menezes
Researcher at University of São Paulo
Publications - 3
Citations - 559
Silvia Lopes de Menezes is an academic researcher from University of São Paulo. The author has contributed to research in topics: Radical & Peroxynitrous acid. The author has an hindex of 3, co-authored 3 publications receiving 518 citations.
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Journal ArticleDOI
Nitrogen dioxide and carbonate radical anion: two emerging radicals in biology.
Ohara Augusto,Marcelo G. Bonini,Angélica M. Amanso,Edlaine Linares,Célio C.X. Santos,Silvia Lopes de Menezes +5 more
TL;DR: A framework for this hypothesis is provided and the potential sources and properties of these radicals that are likely to become increasingly recognized as important mediators of biological processes are discussed.
Journal ArticleDOI
EPR detection of glutathionyl and protein-tyrosyl radicals during the interaction of peroxynitrite with macrophages (J774).
TL;DR: Time dependence studies of free radical formation indicate that intracellular glutathione and unidentified proteins are the initial peroxynitrite targets in macrophages and that their derived radicals trigger radical chain reactions.
Journal ArticleDOI
EPR detection of glutathiyl and hemoglobin-cysteinyl radicals during the interaction of peroxynitrite with human erythrocytes.
Ohara Augusto,Silvia Lopes de Menezes,Edlaine Linares,Natália Romero,Rafael Radi,Ana Denicola +5 more
TL;DR: The results indicate that, through the intermediacy of carbon dioxide and/or hemoproteins, oxidation of glutathione to the glutathiyl radical is likely to be an important consequence of peroxynitrite production in vivo.