S
Simon Murch
Researcher at University of Warwick
Publications - 86
Citations - 8359
Simon Murch is an academic researcher from University of Warwick. The author has contributed to research in topics: Enteropathy & T cell. The author has an hindex of 30, co-authored 85 publications receiving 6860 citations. Previous affiliations of Simon Murch include University Hospital Coventry.
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Lymphonodular hyperplasia of the ileum with increased MHC class II antigen expression and macrophage infiltration in the colon of children with regressive developmental disorder (RDD)
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TAME trial: a multi-arm phase II randomised trial of four novel interventions for malnutrition enteropathy in Zambia and Zimbabwe - a study protocol
Paul Kelly,Lauren Bell,Beatrice Amadi,Mutsa Bwakura-Dangarembizi,Kelley VanBuskirk,Kanta Chandwe,Miyoba Chipunza,Deophine Ngosa,Nivea Chulu,Susan Hill,Simon Murch,Raymond J. Playford,Andrew J. Prendergast +12 more
TL;DR: The TAME trial will evaluate four novel treatments in an efficient multi-arm single-blind phase II design for severe acute malnutrition in children in Zambia and Zimbabwe, once their inpatient treatment has reached the point of transition from stabilisation to increased nutritional intake.
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Matrix expansion and syncytial aggregation of syndecan-1+ cells underpin villous atrophy in coeliac disease.
Camilla Salvestrini,Mark Lucas,Paolo Lionetti,Franco Torrente,Sean James,Alan D. Phillips,Simon Murch +6 more
TL;DR: In this article, the expression of sulphated glycosaminoglycans (GAGs) in coeliac disease (CD) mucosa, as they are critical determinants of tissue volume, which increases in active disease.
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Advances in the understanding and management of autoimmune enteropathy
TL;DR: The centrality of T cell responses in autoimmune enteropathy, rather than B cell autoantibody production, is further suggested by the finding of late-onset gut autoimmunity in APS-1 (autoimmune polyglandular syndrome-1), a condition where negative selection of T cells within the thymus is disrupted due to mutation in the Aire ( autoimmune regulator) gene.